清肺化痰飲輔助治療急性加重期支氣管擴張的臨床研究

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[Abstract]Objective: To evaluate the clinical effcacy Qingfei Huatan Decoction as an adjunct therapy inthe treatment patientswith acute exacerbation bronchiectasis.Method: Atotal 1O6 patients with acute exacerbation bronchiectasis admited toPingxiang Hospital from January 2022 to June 2O24 were selected and randomlyand double-blind divided into the experimental groupand thecontrol group in a1:1ratio, with 53 cases in each group.The control group received conventional western medicine treatment.On this basis,the experimental group was treated with the self-prescribed Qingfei Huatan Decoction.The treatment period was 14 days. The traditional medicine syndrome scores (cough, expectoration,chest tightnes and shortness breath,fever),dyspnea clasification [modified medical research council (mMRC) questionnaire], inflammatory factors (WBC, CRP),lung function and therapeutic efect between the two groups were compared. Result:After14 d treatment,the traditional medicine symptom scoreand mMRC clasification the experimental group were lower than those the control group ( P <0.05).After14d treatment, thelevelsWBC and CRP in the experimental group were lower than those in the control group,the FEV1 ,F(xiàn)VCand FEV,/FVC in the experimental group were higher than those in the control group ( P- <0.05). The total clinical effective rate the experimental group was higher than that the control group ( P <0.05). Conclusion: Qingfei Huatan Decoction as anadjuvant treatment foracute exacerbation bronchiectasis effectively improves symptoms,reduces inflammatory markers,and enhances lung function,demonstrating superior eficacy to conventional western medicine treatment.
[Keywords] Qingfei Huatan Decoction Acute exacerbation BronchiectasisInflammatory factorsLung function
First-author'saddress: Pneumology Department,Pingxiang Hospital , Pingxiang337000,China doi:10.3969/j.issn.1674-4985.2025.21.013
支氣管擴張是一種慢性呼吸系統(tǒng)疾病,特征為永久性支氣管壁的異常擴張,臨床表現(xiàn)為慢性咳嗽、大量咯痰、周期性感染和氣短[。(剩余5349字)