蒼附益坤湯加減輔以來曲唑?qū)Χ嗄衣殉?綜合征不孕癥患者中醫(yī)證候積分、激素 水平的影響
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[Abstract]Objective： To analyze the advantages of Cangfu Yikun Decoction combined with Letrozole in the treatment of polycystic ovary syndrome （PCOS） infertility patients.Method：A total of 86 patients with PCOS infertilityadmitedto Qiandongnan Miaoand Dong Autonomous Prefecture Traditional ChineseMedicine Hospital from January 2O22 to November 2O23 were selected.These patients were randomly divided into two groups，each consisting of 43 cases.The control group received treatment with Letrozole，while the observation group received treatment with Cangfu Yikun Decoction in adition to the control group.The TCM syndrome scores and serum hormone levels between the two groups were compared.Result： The total efective rate and spontaneous ovulation rate of the observation group were 93.02% and 88.37% ，respectively，which were significantly increased compared with the control group of 74.42% and 65.12% ，after treatment， the menstrual cycle，menstrual flow，chest and rib fullness，limb fatigue scores of the observation group were all lower than those of the control group，and the differences were statistically significant （ P <0.05）.After treatment， the estradiol （E2） and endometrial thickness in the observation group increased compared with the control group，while the testosterone （T），uteinizing hormone （LH）， follicle-stimulating hormone （FSH），numberof unilateral follicles，and ovarian volume were lowerthanthosein the control group，with significant differences （ P<0.05 .Conclusion：The treatment of PCOS infertility patientswith Cangfu Yikun Decoction plus Letrozolecan improvethe therapeutic efect and spontaneous ovulation rate，reduce the score of traditional Chinese medicine symptoms，and improve hormone levels.
[Keywords] Cangfu Yikun Decoction Letrozole Polycystic ovary syndromeInfertility
First-author's address：Reproductive Medicine Center， Qiandongnan Miao and Dong Autonomous PrefectureTraditionalChineseMedicineHospital，Kaili556ooo，China doi：10.3969/j.issn.1674-4985.2025.21.011
多囊卵巢綜合征（PCOS）是育齡期女性常見的婦科疾病，以雄激素表達(dá)升高、持續(xù)無排卵、不孕等表現(xiàn)為主，影響著全球 11%～13% 的女性，嚴(yán)重影響了育齡期女性的身心健康[。（剩余6172字）