CRP、NLR對肺炎支原體肺炎患兒發(fā)生慢性咳嗽的預(yù)測價(jià)值

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[Abstract]Objective：To analyze theclinical risk factors of chronic cough in children with Mycoplasma pneumoniae pneumonia （MPP）and explore its predictive indicators.Method：A total of 18O children diagnosed with MPP in the of Beijing from September 2O23 to March 2024 were selected and divided into thecase group （n=52）and the control group （n=128）according to the occurrence of chroniccough.The general information，symptomsand signs，imagingand laboratory indicators of the two groups wereretrospectivelycollected.logisticregression was used toanalyze the influencing factorsofchroniccough. Further，the predictive efficacyof CRPand neutrophil to lymphocyte ratio （NLR） alone and in combination for the occurrence of chronic cough were evaluated by ROC curve.Result：Among 18O children with MPP，52 cases developed chronic cough，with an incidence rate of 28.9% . The proportion of passive smoking history，chronic cough history，allrgic disease history，duration offever ≥7 days，and NLR， CRP levels in case group were higher than those in control group，the differenceswere statistically significant （ P <0.05）. logistic regression analysis showed that history ofallergicdiseases，durationoffever≥7days，NLRandCRPwere independentrisk factors forchronic cough inchildren （ P <0.05）.ROC curve analysis indicated that NLR， CRP and their combined detection could all predict the occurrenceof chronic cough，with AUC of 0.720，0.866 and 0.892，respectively.Conclusion： The individual and combined detection of NLR and CRP have good clinical predictive value for theoccurrence of chronic cough inchildren，thecombined detectionhasthehighestpredictive eficacyandcanbeusedfortheearlyscreening of children at high risk of chronic cough.

[Keywords] Chronic cough Mycoplasma pneumoniae pneumonia Risk factors C reactive protein Neutrophil to lymphocyte ratio

近年來肺炎支原體肺炎（Mycoplasmapneumoniaepneumonia，MPP）成為社區(qū)兒童下呼吸道感染的高發(fā)類型]，同時(shí)也是兒童慢性咳嗽的重要病因之一，這與成人有顯著不同[。（剩余5426字）