雙相情感障礙I型和Ⅱ型患者睡眠特征的差異研究

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Study on the Differences in Sleep Characteristics between Patients with Bipolar Disorder TypeIand TypeI/XIE Rui，F(xiàn)U Songnian.//Medical Innovation of China，2025，22（20）： 183-186

[Abstract]Bipolar disorder （BD）is a chronic mental illness characterized by alternating episodes of mood swings，mania and depresion.Patients often have significant sleep disorders during the course of the disease.Due to the differences in attack types，disease course characteristics and neurobiological mechanisms，there are significant diffrences in sleep characteristics between patients with type BD-I and those with type BD-II. Such differences notonlyafect theemotional regulation and cognitive function of patients，but mayalsobeclosely related to the risk of disease recurrenceand treatment effct.Therefore，accurately identifying and understanding the differences in sleep characteristics between patients with type BD-I and those with type BD- is of great significance for optimizing the treatment strategies ofpatients with diffrentsubtypes.Based onthis，this studysystematicall sorted outthe differences in sleep parameters such as the duration，latency and proportion of rapid eye movement （REM） sleep，the duration and proportion of deep sleep，as wellas the number of micro-awakenings and awakening index between patients with type BD-Iand type BD-II，and explored the influenceof these sleepcharacteristics on the pathological mechanism and clinical intervention.

[Keywords] Bipolar disorder type IBipolar disorder type IISleep structureRapid eye movement sleep Deep sleep

First-author's address： Center of Psychological Medicine，the First Affiliated Hospital of Xinjiang AedicalUniversity，Urumqi83oo54，China

doi：10.3969/j.issn.1674-4985.2025.20.042

雙相情感障礙（bipolar disorder，BD）是一種以抑郁發(fā)作和躁狂或輕躁狂發(fā)作交替出現(xiàn)為特征的慢性精神疾病，其核心表現(xiàn)包括：情緒波動(dòng)劇烈、認(rèn)知功能障礙及社會(huì)功能受損[1-3]。（剩余7557字）