口腔在幽門螺桿菌感染傳播中的地位及作用機制研究

Study on thePosition and Mechanism of Oral Action in the Transmission of Helicobacter pylori Infection/TIANKanglin，HUANGHeyin，MA Fengzhen.//Medical InnovationofChina，2025，22（20）： 177-182

[Abstract] Helicobacterpylori infection iswidespread，with approximately 50% of the global population being infected.The infectionrate is closely related to geographical regions，demographic characteristics，economic conditions，hygiene habitsand the degreeofclosecontact of infected individuals.The infection rate is generally higher in developing countries.Although the transmission routes of Helicobacter pylori have been widely studied， there is a lack of direct evidence for its recognized transmission routes.More and more evidence shows that oralcavity maybe the mainrouteof transmission，butthe position androle oforal cavityin transmisionis still inconclusive.This review aims tooutline the potential positionand mechanism of action of theoral cavityin the transmissionofHelicobacterpylori，withtheexpectationof providingnew ideas fortheblockingof Helicobacterpylori transmission.

[Keywords] Helicobacter pylori Oral cavity Infection mechanism Mechanism of transmission

First-author'saddress：DepartmentofGeneralMedicine，Binzhou Medical UniversityHospital Binzhou 256603， China

doi：10.3969/j.issn.1674-4985.2025.20.041

幽門螺桿菌與胃癌的發(fā)生高度相關(guān)，中國胃癌發(fā)生率及死亡率均占到了全球的 40% 以上，嚴重威脅人民健康。（剩余15322字）