血小板抗體聯(lián)合凝血功能檢測在圍手術期輸血治療中的指導作用分析

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Analysis of the Guiding Effect of Platelet AntibodyCombined with Coagulation Function Detection in Perioperative Blood Transfusion Therapy/CHEN Liwan， CHEN Zijun，MA Zuoyun. //Medical Innovation of China，2025，22（20）：124-127

[Abstract]Objective： To explore the guiding effect of platelet antibody combined with coagulation function detection in perioperative blood transfusion therapy.Method：The clinical data of 68 patients with perioperative bloodtransfusion in in Hospital ofthe Second Xiangya Hospital CSUfromMarch 2O23 to March 2024 were retrospectivelyanalyzed，and they were grouped according to different blood transfusion guidance methods. The control group （ n =34） received blood transfusion based on the results of coagulation function detection，and the observation group （ n =34） received blood transfusion guidance based on platelet antibody combined with coagulation function detection.The infusion conditions of blood components，the coagulation function before and 24 hours after blood transfusion， platelet corrected count increment （CCI） and the occurrence of complications were compared between the two groups.Result：There were no statistically significant diferences in platelet，red blood cell suspension，cryoprecipitate，fresh frozen plasma and total blood transfusion volume between the two groups （ P> 0.05）.24 hoursafter blood transfusion，there were nostatistically significant differences in TT，PT，APTTand FIB between the two groups （ P， >0.05）.1 h and 24 h after blood transfusion，the platelet CCI in the observation group were significantly higher than thosein the control group（ P<0.05） .There wasno statistically significant difference inthe incidence of complications between the two groups （P>0.05 ）.Conclusion：Platelet antibody combined with coagulation function detection has guiding value in perioperative blood transfusion therapy and can improve platelet CCI.

[KeyWords] Perioperative period Blood transfusionPlatelet antibodyCoagulation function

First-author's address：Department of Blood Transfusion， in Hospital of the Second Xiangya Hospital CSU， in 541001， China doi： 10.3969/j.issn.1674-4985.2025.20.029

輸血是臨床上多用于治療嚴重創(chuàng)傷、大型手術或急性大出血患者的常用手段，通過成分血輸注能夠快速補充患者體內(nèi)缺乏的紅細胞、凝血因子及血小板，改善攜氧能力和凝血功能，挽救急危重癥患者生命[1-2]。（剩余6272字）