幽門螺桿菌生物膜與傳染鏈的關(guān)聯(lián)及潛在作用

Associationand Potential Role of Helicobacter pylori Biofilmsand Transmission Chain/HUANG Heyin， IANKanglin，MA Fengzhen.//Medical Innovation of China，2025，22（20）：162-167

[Abstract] Helicobacter pylori （Hp）transmisson routes are key factors influencing the epidemiological characteristicsofHp infections inpopulations，andHpbiofilmformation iscriticalforinfectionpersistenceand transmission eficiency.As complex microbial aggregates，Hp biofilms undergo three important phases：aggregation， growth，andfragmentation.Hpbiofilms havebeenassociated withoral-oral，fecal-oral，andother transmission routes.Hpbiofilmsareassociated withoral-oral，fecal-oral，andotherroutesof transmisson，andthepotential mechanismsofactionare primarilythrough theirabilitytoadheretoHptofacilitateHpcolonizationandsurvival，to assist Hp in counteracting antibioticsand the host immune system，and to enhance survival and transmision through aggregation.

[Keywords] HelicobacterpyloriBiofilmTransmissionchain

First-author'saddress：Department ofGeneral Medicine，Binzhou Medical University Hospital， Binzhou 256603，China

doi：10.3969/j.issn.1674-4985.2025.20.038

幽門螺桿菌（ Hp ）是一種微需氧革蘭陰性桿菌，與多種胃相關(guān)疾病有關(guān)，包括消化性潰瘍、慢性胃炎、胃食管反流病、功能性消化不良和胃腺癌等。（剩余16596字）