慢性阻塞性肺疾病急性加重患者在院期間紅細(xì)胞分布寬度與預(yù)后相關(guān)性研究

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udyon theCorrelation BetweenRed Blood Cell Distribution WidthandPrognosis inPatients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease During Hospitalization

WANGYuan1，XINCaixia1，YANGHaiying1，CHENDan2，HUANGNa3 （1.DepartmentofespratoryndCriticalCare edicine，enshouCountyeople'sHspital，Renshou6Ooo，ca，in； 2.Respiratory Department of Yunchang Hospital in Renshou County，Renshou 62o5oo，Sichuan，China； 3.DepartmentofRespiratoryandCritical Care Medicine，theFirst Afiliated Hospital of Chengdu Medical College， Chengdu ，Sichuan， China）

Abstract：ObeixplooelolodcellstioDndogosofcuaceb obstructivepulmoarydseaseECOpatintsrigospitalizoMetodsTcaldtaofECOpatintsdmitedttesie careunitfromJanuary208toDecember2O19wereextractedfromtheMMC-IVpublicdatabase.Accordingtothelevelofredblodcel distribution width，they were divided into high RDW group （ R D W>1 5 % ）and normal RDW group （ R D W？ 1 5 % ）.The general conditions of AECOPD patientsintetoousreomparedKaplaneieretdsedtodrateurvivaluretoompareefreceofyeariale betweenthetwogroups.ROCcurvewasusedtoevaluatethediagnosticvalueofRDWinthedeathofAECOPDpatientswithin1year.Cox proportionalhadegressoaalysasdtaltsfctocigtathfCOpatintsResultsotalof patientswereicludedCompeditheoalDoup，tepropoiofpertesioabetesartfurendSOFsoeig RDWgroup were higher than thosein the normal RDW group（ .The1-yearmortalityof patientsinthehighRDWgroup（80.57 % ）washigher than that in the normal RDW group （ 7 1 . 0 9 % ） ，P=0.007）.The results of ROC curve showed that the area under the curve of RDW predicting thedeathfACOtisinaras85%.2）tsivi7esefitndf valuewas 1 5 . 8 % .TheresultsofCoxproportionalhazardregressionanalysisshowedthatRDWwasanindependentriskfactorforpredictingthedeath fAECOPDpts（76.543）CcueasefDedepdtsfct prognosis of patients with AECOPD，which can beused to judge the risk of death in patients with AECOPD.

Keywords：MIMIC-IV database；Red blood cell distributionwidth；AECOPD；Prognosis

慢性阻塞性肺疾病急性加重（acuteexacerbationof chronic obstructive pulmonary disease，AECOPD）是導(dǎo)致COPD患者住院治療的主要原因，且與患者預(yù)后不良有關(guān)。（剩余8480字）