超聲引導(dǎo)下射頻消融術(shù)治療混合性甲狀腺結(jié)節(jié)對(duì)患者術(shù)后應(yīng)激及體積縮小率的影響

Effect of Ultrasound-guided Radiofrequency Ablation on Postoperative Stress and Volume Reduction Rate of Patients with Mixed Thyroid Nodules/MIN Yonghua， ZHU Yu， JIANG Hui. //Medical Innovation of China， 2025， 22（10）： 050-053

[Abstract]Objective： To explore the efect of ultrasound-guided radiofrequency ablation on postoperative stressandvolumereductionrateofpatients withmixed thyroidnodules.Method：Atotalof 100patients with mixed thyroid nodules admitted to theFifth Hospital of Nanchang from January 2022 to April 2023 were retrospectively selected and divided into ethanol ablation group （n=47） and radiofrequency ablation group （n=53） according to different microtraumatic treatment methods.The ethanol ablation group underwent ultrasound-guided anhydrous ethanol ablation， and the radiofrequency ablation group underwent ultrasound-guided radiofrequency ablation. The stress condition， nodules volume reduction rate and clinical efficacy of the two groups were compared. Result：Compared with ethanol ablation group， the levels of Creactive protein （CRP），interleukin-6 （IL-6）and

tumor necrosis factor- α （TNF- α ）1 d after surgery in radiofrequency ablation group were lower （P<0.05） ·Compared with ethanolablation group， the nodulesvolume reduction rate in radiofrequency ablation groupl month， 3， 6， 9， 12 months after surgery were higher （ （P<0.05） . The total efective rate of radiofrequency ablation group was 92.45% ， which was higher than 72.34% of ethanol ablation group （P<0.05） . Conclusion： Ultrasound-guided radiofrequency ablation in the treatment of mixed thyroid nodules can efectively reduce the stressresponseof patients and reduce the nodules volume.

[Key words] Radiofrequency ablation Mixed thyroid nodules Postoperative stress Volume reduction rate

First-author's address： Department of Ultrasound Room， the Fifth Hospital of Nanchang， Nanchang 330000， China

doi：10.3969/j.issn.1674-4985.2025.10.012

甲狀腺結(jié)節(jié)是甲狀腺內(nèi)的異常增生組織，可在甲狀腺組織內(nèi)形成一個(gè)或多個(gè)小的團(tuán)塊，混合性甲狀腺結(jié)節(jié)指的是結(jié)節(jié)內(nèi)部同時(shí)包含囊性、實(shí)性組織結(jié)構(gòu)，部分患者伴有鈣化或出血性改變-2]。（剩余5816字）