潰瘍性結(jié)腸炎致骨質(zhì)疏松癥的發(fā)病機(jī)制研究進(jìn)展

[Abstract]Ulcerativecolitis（UC）isaprevalentinflammatory boweldiseasethatisassociated with multiple systemiccomplications.Withthegrowingaging populationinChina，theprevalenceofosteoporosis（OP）hasreachedthe highestlevelworldwide. UCcanleadtosecondarypathologicalchangesthatdisruptskeletalhomeostasisandreducebonemineraldensity，therebysignifiantly increasingtheriskofOPinfectedpatients.ThisreviewexplorestheunderlyingmecanismsofUC-inducedOP，includingmicronutrientdeficiencyidativess，fmtoysones，nditestialcoaldiosismmagentols article alsoaims to provide atheoretical foundation for the preventionand management of OP in patients with UC.

[Key words] Ulcerative colitis；Osteoporosis；Pathogenesis mechanism；Bone density

潰瘍性結(jié)腸炎（Ulcerativecolitis，UC）是臨床上一種常見的炎癥性腸病，主要見于乙狀結(jié)腸、降結(jié)腸、直腸，嚴(yán)重時(shí)可累及全結(jié)腸。（剩余10894字）