瑞馬唑侖與丙泊酚對老年腹腔鏡手術(shù)患者麻醉誘導(dǎo)期血流動力學(xué)及術(shù)后認(rèn)知功能的影響

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[Abstract]ObjectiveTo investigatetheefectsof RemazolamandPropofolonhemodynamicsand postoperativecognitive functionduringanesthesiainductioninelderlypatientsundergoinglaparoscopicsurgery.Methods116elderlypatientsundergoingelectivelaparoscopicsurgeryinYibinHospital，WestChinaHospitalSichuanUniversityfromDecemberO22toMarch4were lectedasthestudysubjectsanddividedintoobservationgroupandcontrolgroupacordingtorandomnumbertable，with58casesin eachgroup.Remazolamwasusedforanesthesiainductionandmaintenanceintheobservationgroup，andPropofolwasusedforanesthesianductionandmaintenanceinthecontrolgroup.Thehemodynamicindicatorsandthequalityofrecoveryattwodierenttime points werecompared，andtheoccurrnceofadversereactionsandcognitivefunctionscoreswererecorded.ResultsIntheobservationgroup，thehartateandmeanarterialpressureimmediatelyaftertrachealintubationand3minafterintubationwerehigherhan those in the control group （ P<0.05 ），the spontaneous respiratory recovery time，eye-opening time and extubation time were shorter thanthose in thecontrol group（ P<0.05 ），thecognitive function scores at1d and3d after operation were higher than thosein the control group （P<0.05 ），the total incidence of adverse reactionswaslower than that in thecontrol group（ P<0.05 ）.Conclusion ComparedwithPropofol，Remazolamisusedinelderlylaparoscopicsurgery，withmorestableintraoperativebloodflowfluctuations， fasterpostoperativerecoveryndfewradverseeactions.Forpatientswithlsscognitivefunctio，itisstablefolderlypatits withrelativelyweak bodyand easilyunstable hemodynamics.

[Key words] Remazolam；Propofol；Laparoscopic surgery；Hemodynamics；Cognitive function

腹腔鏡手術(shù)是臨床常用手術(shù)方法，全麻手術(shù)在老年患者中的應(yīng)用越來越普遍[1]。（剩余8812字）