吲哚菁綠熒光顯像技術在膽道閉鎖中的應用

基金項目：廣州市衛(wèi)生健康科技項目（20231A011040）；廣州醫(yī)學院科研基金項目（2023ekky007）

Abstract：Biliaryatresia（BA）ischaracterizedbyprogresiveinflammationandfibrousobstructionofbileducts，ultimately leading tocholestaticlivercirhosis.KasaisurgeryisthestandardprocedureforthetreatmentofBA，andearlydiagnosisisakey influencingfactorfortheprognosisofBA.Indocyaninegree（ICG）isanear-infraredphotosensitivedyethatiseficientlyand selectivelyabsorbedbyepatocytesafterintravenousinjection，anditenters theintestineviabileandisexcretedwithtefecesin thefreeform，withafavorablesafetyprofile.Inaddition，ICGcanemitfluorescenceundernear-infraredlight，whichanbe capturedbycamera instrumentsandconvertedintovisualimages，andICGfluorescence imaging technologycanreflectthe intraoperativesituationinrealtimeandsignificantlyimprovethesuccessrateofthesurgicalprocedure.Thisarticlereviews the advancesintheapplicationof ICGinearlypreoperativediagnosis，intraoperativeimaging，andpostoperative liver function assessment in recent years.

KeyWords：Biliary Atresia；Indocyanine Green;Early Diagnosis

Research funding：Guangzhou Municipal Health Science and TechnologyProject（2O231A011040）；Research Fundof Guangzhou Medical University（2023ekky007）

吲哚菁綠（indocyaninegreen，ICG）是一種近紅外可見的熒光三碳菁染料，1956年由美國食品和藥物管理局批準使用。（剩余19683字）