0.05 ,治療后2組CDCA5表達(dá)較于治療前均有所降低,且觀察組較對照組更低( P<0.05 );對2組患者治療后進(jìn)行2年隨訪發(fā)現(xiàn),觀察組患者生存率較于對照組更高,但復(fù)發(fā)率較對照組更低( P<0.05 ;治療前2組患者腫瘤灶直徑差異無統(tǒng)計學(xué)意義( P>0.05) ,治療半年、1年、2年后觀察組患者腫瘤灶直徑較對照組更小 P<0.05 ;治療前2組患者AFP、CEA指標(biāo)差異無統(tǒng)計學(xué)意義( P>0.05 ,治療后觀察組AFP、CEA指標(biāo)較于對照組更低( P<0.05 。結(jié)論早期肺癌患者使用CT引導(dǎo)射頻消融術(shù)診治能夠有效改善患者腫瘤標(biāo)志物指標(biāo)及CDCA5表達(dá)、提高生存率、降低復(fù)發(fā)率,對患者康復(fù)具有較高臨床效果,值得推廣應(yīng)用。-龍源期刊網(wǎng)" />

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CT引導(dǎo)射頻消融術(shù)在早期肺癌患者中的臨床應(yīng)用效果

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Clinical efects CT-guided radirequency ablation in patients with early-stage lungcancer Wang Kunliang"Yan Jin,Yuan Junhua.*horacic DseaseHospital,Zhumdian,

【Abstract】 ObjectiveTo analyze the application efect CT-guided radirequency ablationon early lung cancer.MethodsNinety-eight patients with early-stage lung cancer whoreceived treatment inour hospital from July 2022 to July 2O23 were selectedas theresearchsubjectsand were divided into thecontrol group (n=45)and the observation group (n=53)acording to the numerical ranking tablemethod,and thepatients in thecontrol group underwent conventional treatment,while theobservation group underwent CT-guided radirequency ablation,and the patients the two groups were examined in terms their CDCA5 expresion,survival rate,and recurrnce rate, Tumor markers [alpha-fetoprotein(AFP),carcinoma embryonicantigen (CEA)],and thediameter tumor foci were compared.ResultsThere was no significant diference in the expression CDCA5 between the two groups before treatment ( P>0.05 ).After treatment,the expression CDCA5 in the two groups was lower than that before treatment,and the observation group was lower than the control group ( P<0.05 ).After2 years follow-up,the survivalrate observation group was higher than control group,butthe recurrence rate was lower than control group ( P <0.05).There was no significant diference in tumor lesion diameter between the two groups before treatment ( P> 0.05),and the tumor lesion diameter the observation group wassmaler than that the control groupafter six months,one year and two years treatment ( P <0.05).Before treatment, there was no significant difference in the AFP and CEA indexes between the two groups( P >0.05),and after treatment,the AFP and CEA indexes in the observation group were lower than those in thecontrol group (P<o.o5).conclusionct-guided radirequency="" ablationin="" early-stage="" lungcancer="" patients="" can="" effectively="" improve="" tumor="" marker="" indicators="" and="" cdca5="" expression,="" survival="" rate,reduce="" recurrencerate,which="" have="" ahighclinicalefecton="" patients'recovery,and="" is="" worthy="" application.=""

肺癌是源于患者氣管、支氣管黏膜、腺體的臨床常見肺部原發(fā)性惡性腫瘤,目前確切病因尚未明確,主要致病因素包括吸煙、職業(yè)暴露、空氣污染、飲食、肺部病史等,早期患者無顯著癥狀,表現(xiàn)為無痰或少痰的陣發(fā)性刺激性干咳,隨著病情發(fā)展會造成患者組織壞死,甚至死亡等,對患者生命安全造成嚴(yán)重影響[1-3]。(剩余5973字)

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