中性粒細胞絕對值計數(shù)與血清白蛋白比值對中晚期食管鱗狀細胞癌術(shù)后患者預后的作用
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中圖分類號：R735 文獻標識碼：A DOI：10.3969/j.issn.1006-1959.2025.12.013
文章編號：1006-1959（2025）12-0065-06
Role of Neutrophil-to-AlbuminRatio inPredicting PrognosisofPatientswithAdvanced Esophageal Squamous Cell Carcinoma After Surgery
ZHAOJiqi，ZHOUMengxi1，LYUYinl，DENGJiaying2，XULei'，DONGYaqin1，ZHULiyang，WANGYichun’，KANGei （1.DepartmentofadiatioOncolgytheirstAfiatedHospitalofAnuidicalUivesityHefeiO，Anin; 2.Department of Radiation，F(xiàn)udan University Shanghai Cancer Center，Shanghai 2Ooo32， China）
Abstract：ObjetieTevauatetherogosicaluefpreoperativepperalblodeutrophiltoabmiatio（NAR）ipatintswith esophagealsasellrocalgeeJatar4titsioeall carcinomafedicalesetionfrothFstAfliatedHspitalofAnuMedicalUniversiynd6patientsihesoagealuaocel carcinomaafteradicalresetonfromFudanUniversityShanghaiCancerCenterwereselecedassubjectsTheotialutoffvalueofNRws analyzedby X-Tile softwareand divided into low score group （NAR <0 .1） and high score group （NAR≥O.1）.The clinical data of the two groups were compared，ndhgostcoeroudsodeleaplaeeededteald testwasefletei sungical procedure，degree of diffrentiation，tumor locationand TNM stage between the two groups（ P> 0.05）.The median follow-up time was 40 months（range-56months），andthemedianOSwas50O（95%C38.5-61.5）moths.ThemedianOofthelowsoregoupas7（95%C 34.8-79.2）motsntemedanOSoftegoreos25%9oe，ndearuialaesf the low-score group were 85.9 % 60.5% ，49.8%，and 41.0% ，respectively，while the1-，3-， 5- ，and 10-year survival rates of the high-score group were73.4 % ，46.6 % ，36.0%，and23.8 % ，respectively.Coxunivariateanalysisshowedthatgender，smoking history，drinkinghistory，TNMstageand NARwerethegosticctosfOO）.Ftouiaeealodaooade indepedentsctogosplaalisodabsiota Conclusion High NAR （NAR ?0.1 ） is an idependent risk factor forOS in patientswith esophageal squamous cell carcinoma.Preoperative NAR is a convenient and efective indicatorfor predicting postoperative survival of esophageal squamous cellcarcinoma.
Keywords：Esophageal squamous cell carcinoma; Neutrophil-to-albumin ratio; TNM stage
食管癌（esophagealcancer）在我國男性和女性中的發(fā)病率分別排在第五位和第十位，且隨著年齡增長，食管癌發(fā)病率呈逐漸上升趨勢，并于80＼～84歲達到峰值。（剩余8713字）