3 次仍未接種。研究組患者按照0-1-6月免疫程序進(jìn)行乙肝疫苗接種,在規(guī)定日期內(nèi)連續(xù)完成3次接種。采用多因素Logisitic回歸分析乙肝疫苗全程接種的影響因素,比較兩組乙肝表面抗原( H B s A g )陽性率及乙肝表面抗體(HBsAb)陽性率。結(jié)果單因素分析顯示,性別及婚姻狀況對(duì)成人乙型肝炎疫苗全程接種影響不大( P>0 . 0 5 : ;而年齡、文化程度、乙肝家族史、乙肝防護(hù)行為、乙肝知識(shí)認(rèn)知情況及職業(yè)等均與成人乙型肝炎疫苗全程接種間存在較大影響 ( P>0 . 0 5 ) 。多因素Logistic回歸分析表明,年齡、文化程度、乙肝家族史、職業(yè)、乙肝知識(shí)認(rèn)知情況均為成人乙肝疫苗全程接種的獨(dú)立影響因素( P < 0 . 0 5 。研究組HBsAg陽性率低于對(duì)照組,HBsAb陽性率高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義( P<0 . 0 5 ) 。結(jié)論成人乙肝疫苗全程接種的相關(guān)影響因素較多,有必要加強(qiáng)健康宣教,提高疫苗全程接種率及免疫效果,降低乙肝病毒感染風(fēng)險(xiǎn)。-龍?jiān)雌诳W(wǎng)" />

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成人乙型肝炎疫苗全程接種的影響因素及免疫效果分析

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中圖分類號(hào):R186 文獻(xiàn)標(biāo)識(shí)碼:A文章編號(hào):1006-1959(2025)09-0078-04

DOI:10.3969/j.issn.1006-1959.2025.09.014

Abstract:ObetieTalyfuencfactosdiuetsfoleousevaiatioofatiBccniul.d totaofOdultsoerevaciateditepatitisBvaccifrJuartecebr2inXiajaCountyCenterfoDiseasCotrolad Preventionwersacorsoftcecadt stdgoupdo)atsioodoeatatiated contactedhefooretan3iesadstilddoteeevaciatioatitsiesudygouerevaccatedithepatiis acordingtotOothuatioprga,dheaiatiosreopleediouslwiinpeifddateuliate Logisitic regression analysis was used to analyze the influencing factors of hepatitis B vaccination. The positive rates of hepatitis B surface antigen (HBsAg)andhepatitisBsurfaceantibody(HsAb)werecomparedbetweethetwgroups.ResultsUnivariateanalysisshowedthatgenderand marital statushad little effect onadult hepatitisB vaccination( P>0 . 0 5 ),whileage,educationlevel,familyhistoryof hepatitisB,hepatitisBprotection behavior,hepatitis B knowledge cognition and occupation had great influence on the whole course vaccination of hepatitis B vaccination in adults ( P >0.05).MuliLstilodatutiolevelltopaiistio hepatitis B wereindependent influencing factors for thewhole course vaccinationof hepatitis B vaccination inadults( P - <0.05).Thepositive rate of HBsAginthsudygroupaslowerthanthatinthecontrolgroupandtheposiverateofHsAbwashigherthanthatinthecontrolgroup,te differences were statistically significant( .Conclusion There are many related factors affecting the whole course vaccination of hepatitis B vainendulralcatioplouaiateduf hepatitis B virusinfection.

Key Words:Adult; Hepatitis B vaccine;Whole course vaccination; Influencing factors;Immune effect

乙型肝炎病毒(HBV)作為DNA病毒之一,屬于嗜肝DNA病毒科,就目前所知道的情況來看,它僅對(duì)人類和猩猩具有易感性。(剩余4568字)

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monitor