基于“脾腎陽虛，痰濁阻滯”理論探討神經(jīng)根型頸椎病與線粒體自噬的關(guān)系

Exploring the Relationship between Cervical Spondylotic Radiculopathy and Mitophagy Based on the Theory of "Yang Deficiency of Spleen and Kidney， Blockade of Phlegm-Turbidity"/WANG Yue， DONG Ping，YAO Guangyuan， HU Kai. //Medical Innovation of China， 2025， 22（12）： 180-184

[Abstract]The pathogenesis and treatment of cervical spondylotic radiculopathy are the focus of medical research at present.Mitophagy is the process of removing or degrading damaged and aged mitochondrion. Mitophagy plays an important role in the occurrence and development of intervertebral disc degenerative change and neuropathic pain， and both intervertebral disc degenerative change and neuropathicpain are closely related to cervcal spondylotic radiculopathy，so it is inferred that mitophagy is closely related to the onset of cervical spondyloticradiculopathy.According totraditional Chinesemedicine， the main pathogenesis ofcervical spondylotic radiculopathy is yang deficiency of spleen andkidney and blockade of phlegm-turbiditywhich is similar to mitophagy atthe microscopic level.Therefore，based on the theory of "Yang deficiency of spleen and kidney， blockade of phlegm-turbidity"，this paper willexploretherelationshipbetween mitophagy andcervical spondylotic radiculopathy fromthe perspective of traditional Chinese medicine and western medicine，providing anew direction and target for the research and treatment of cervical spondylotic radiculopathy.

[Key words] Cervical spondylotic radiculopathy Yang deficiency of spleen and kidney Blockade of phlegm-turbidityMitophagy

First-author's address： College of Traditional Chinese Medicine， Inner Mongolia Medical University， Iohhot 010110， China

doi：10.3969/j.issn.1674-4985.2025.12.043

神經(jīng)根型頸椎?。╟ervical spondylotic radiculopathy，CSR）占頸椎病的 60%～70% ，是頸椎及其附屬結(jié)構(gòu)退變壓迫神經(jīng)根出現(xiàn)頸部不適，伴有上肢放射痛與麻木的常見頸椎病，嚴重影響患者的身心健康。（剩余8726字）