吡柔比星染色定位在非肌層浸潤性膀胱癌手術(shù)治療中的應(yīng)用

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Application of Pirarubicin Staining Localization in the Surgical Treatment of Non-muscle-invasive Bladder Cancer/CHEN Xiuxiang， LIU Yu， XU Jian. /Medical Innovation of China， 2025， 22（12）： 154-158

[Abstract]Objective： To analyze the application effect of Pirarubicin （THP） staining localization in the surgical treatment of non-muscle-invasive bladder cancer （NMIBC）.Method： The clinical data of 83 NMIBC patients admitted to the Department of Urology， al Chinese Medicine Hospital from January 2022 to July 2023 were retrospectivelyanalyzed.They were divided intotwo groups according todifferent treatment methods. The control group （ n =40） was treated with transurethral resection of bladder tumor， and the observation group （n=43） underwent THPstaininglocalizationby irigationof bladder30min before surgery，andthen transurethralresection of bladder tumor was performed.Theoperation status， tumor markerslevels，secretory regulatory factors levels， tumor recurence and progression were compared betweenthetwo groups.Result：There were no significant diferences in operation time， intraoperative blood loss and postoperative hospital stay between the two groups （ P>0.05 ）. The levels of tumor markers andsecretoryregulatoryfactors intheobservationgroup4weeksaftersurgerywerelowerthanthose in the control group， the differences were statistically significant . There were no significant differences in the incidence of postoperative complications and the rate of tumor progression between the two groups （ P>0.05 ）.The recurrence rate of tumor in the observation group was 4.65% ， which was lower than 25.00% in the control group， the difference was statistically significant （P<0.05） . Conclusion： THP staining localization before transurethral resection of bladder tumor in NMIBC patients can reduce the levels of tumor markers and tumor recurrence rate.

[Key words] Transurethral resection of bladder tumorPirarubicin Non-muscle-invasive bladder cancer

First-author's address： Department of Urology， al Chinese Medicine Hospital， 551700， China

doi：10.3969/j.issn.1674-4985.2025.12.037

膀胱癌是臨床常見泌尿系腫瘤，是發(fā)生于膀胱黏膜的腫瘤，好發(fā)于男性。（剩余6466字）