HER2陽性乳腺癌治療的研究進(jìn)展

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Research Progress in the Treatment of HER2-positive Breast Cancer/FAN Xuejiao， WU Tao， YUAN Ye.//Medical Innovation of China， 2025， 22（11）： 184-188

[Abstract]HER2-positive breast cancer is a highly aggressive tumor subtype， and its treatment strategies have beenahot topic inthe fieldof cancer research and haveundergone significant changes in thepastfew decades. With the in-depth understanding of HER2-positive breast cancer， treatments for HER2-positive breast cancer are continuously innovating，significantly improving thesurvival prognosis of patients.This article reviewsthe latest research progress in the field of HER2-positive breast cancer treatment， including the development of targeted drugs， immunotherapy， cell therapy， and new drugs.

[Key words] HER2-positive breast cancer Targeted therapy Immunotherapy Treatment strategy

First-author's address： Department of Breast Surgery One， Affliated Tumor Hospital of Xinjiang Medical University， Urumqi 830ooo， China doi ： 10.3969/j.issn.1674-4985.2025.11.041

人表皮生長因子受體2（HER2）陽性乳腺癌占所有乳腺癌患者的 20%～30% ，其特點(diǎn)是HER2基因擴(kuò)增和蛋白過表達(dá)，與疾病的惡化和預(yù)后不良密切相關(guān)-]。（剩余10182字）