基于多元統(tǒng)計(jì)分析和貝葉斯網(wǎng)絡(luò)的精神分裂癥合并超重或肥胖患者的中醫(yī)證候分析

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本文引用：.基于多元統(tǒng)計(jì)分析和貝葉斯網(wǎng)絡(luò)的精神分裂癥合并超重或肥胖患者的中醫(yī)證候分析[J].湖南中醫(yī)藥大學(xué)學(xué)報(bào)，2025，45（4）：711-718.

[關(guān)鍵詞]精神分裂癥合并超重或肥胖；因子分析；聚類分析；多元統(tǒng)計(jì)分析；貝葉斯網(wǎng)絡(luò)；中醫(yī)證候[中圖分類號]R259 [文獻(xiàn)標(biāo)志碼]A [文章編號]doi：10.3969/j.issn.1674-070X.2025.04.019

[Abstract]Objective Toinvestigate the Chinese medicine patem lawsinschizophreniapatientswith overweightor obesity.MethodsAcros-sectionalstudywasonduted，collctingTCMpatteminformationof36Oshizophreniapatintswith overweightorobesitywhovisitedoutpatientclinicsorwerehospitalizedattheThirdHospitalofHeilongjiang Province（Mental andNeurologicalDiseaseHospitalofHeilongjiangProvince）anditssub-centersfromJune2O23toJune2O24.Multivariate statisticalanalyses，includingfactoranalysisandclusteranalysis，wereemployedfordimensionalityreductionandcategozation. BasicTCM patern elements （diseaselocationandnature）andpattem identificationtypeswereextractedandsummarized.Bayesian networkwasusedtopreliminarilyexploretherelationshipsofpaterns—pattrntypes—clinicalindex.ResultsNinepatern factorsandfivepatterntypeswereidentified，withtheafectedorgansinvolvingtheliver，galbladder，heart，splee，and kidney.Diseasenaturesincludeqideficiency，yang deficiency，phlegm，dampnes，qistagnation，bloodstasis，qideficiency， andfire-heat.Theidentiedpaternsincludedeficiencyoftheheartandspleen，dualdeficiencyofqiandyin，bloodstasis duetoqi deficiency，yangdeficiencyof thespleenandkidney，anddampnessstagnationtransforming intofire.Whenthe targetvariablewassetasthebodymassindex（BMI）≥24kg/m，theposteriorprobabilitiesforthepaternsofyangdeficiency ofthespleenandkidney，deficiencyoftheheartandspleen，anddampnesstransformingintofirewerethetoptree. Conclusion TheTCMpaternsinschizophreniapatientswithoverweightorobesitycanbepreliminarilycategorizedintofive types.Among them，yangdeficiencyofthesplenandkidney，dficiencyoftheheartandspleen，anddampness transfoing intofirearecommonpatternsasociatedwithhigherBMI.Multivariatestatisticalanalysescanbeusedtoexplorethepatten lawsin schizophrenia patients with overweight or obesity.

[Keywords]schizophreniawithoverweightorobesity；factoranalysis；clusteranalysis；multivariatestatisticalanalysis; Bayesian network; Chinese medicine pattern

精神分裂癥是精神科常見病，以認(rèn)知、思維、行為、情感等方面的功能障礙為主要表現(xiàn)，具有致殘率高、疾病負(fù)擔(dān)重等特點(diǎn)。（剩余8928字）