鐵死亡中鐵穩(wěn)態(tài)在阿爾茨海默病的研究進(jìn)展

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Research progress of the role of iron homeostasis in ferroptosis in Alzheimer's disease
Luo Chenliang1,2,Wu Guiyou1,Li Zhenzhong2,Huang Zhongshi3 ** (204號(hào) 1 Graduate School,Guangxi UniversityofChinese Medicine,Nanning5302oo;ScholofPharmacy,YoujiangMedical Universityfor Nationalities,Baise533ooo;ScholofBasic Medicine,Youjiang MedicalUniversityforNationalities,Baise533000 **Corresponding author:Huang Zhongshi,email:hzs1004@ 163.com
[Abstract]Feroptosisisadticttypeofcellardemiefrequentlyidentifedinthecerebraltissuesofindividualsflite withAlzheimerssease(AD)Itontributestothdvancementofseveraldsorders,ncudingdementiaalignancies,doste porosis,ithtdieeiallprdsoatediitisiiftldiesasaedis orderedironeosisisalisoosisoiseialialusfo ing mitochondialenergyproduction,synthesizingmyelinandneurotransmiters,andfacilitatingotherfundamentalphysiologicalfunc tions.Thisaticleofesanetesiveanalysisoftheiteractionsaongaycriticalelementsrelatedtoironomeostasis,fotosis, and the common pathogenic mechanisms linked to Alzheimer's disease (AD).
[Keywords] Alzheimer's disease,F(xiàn)erroptosis,Iron homeostasis,Iron homeostasis regulators
鐵死亡是一種鐵依賴性的細(xì)胞死亡形式,它在形態(tài)學(xué)、生物化學(xué)、基因和蛋白表達(dá)水平上,均不同于其他形式的細(xì)胞死亡[]。(剩余15822字)