0.05 );A組口鼻腔干燥評分、咽喉疼痛評分均低于B組,差異有統(tǒng)計(jì)學(xué)意義( P<0.05 );兩組動脈氧分壓、動脈二氧化碳分壓及ΔpH 值比較,差異均無統(tǒng)計(jì)學(xué)意義( P>0.05 );兩組氧療期間不良反應(yīng)發(fā)生率比較,差異無統(tǒng)計(jì)學(xué)意義( P>0.05) ;兩組ICU入住時間、住院時間及隨訪28d預(yù)后不良患者占比比較,差異均無統(tǒng)計(jì)學(xué)意義( P>0.05, 。結(jié)論 40L/min 氧療流速的HFNC干預(yù)可顯著提高老年重癥肺炎患者的舒適度,對患者撤機(jī)成功率、血?dú)庵笜?biāo)及短期預(yù)后無明顯影響。-龍?jiān)雌诳W(wǎng)" />

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HFNC不同氧療流速對老年重癥肺炎撤機(jī)困難患者撤機(jī)成功率、血?dú)饧邦A(yù)后的影響

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Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning

Tang Gaorou1,Lu Guoyu (20 1 Department of Emergency Medicine,the Second Afiliated Hospital of Bengbu Medical University,Bengbu233040; 2 Department of Emergency Medicine,the First Afiliated Hospital of Bengbu Medical University,Bengbu233004 **Corresponding author:Lu Guoyu,email:13033013637@163.com

[Abstract]OjectiveToanalyzetheefectsof diferentflowratesinhigh-flownasalcannulaoxygentherapyonthesuccessrate of weaning,bloodgandprogosisinelderlyatintswiteverepeoaanddicultyinweaning.MethdsAetrosptieaalis wasconductedontedtaof8ederlypatientswithseverepeumoaanddiultyinweaningowereadmiedtotesecodlite HospitalofengbuMedicalUniversitfromNovember22toctobr24.Allpatintseollderegivensequntialhighowasalan nulaafterextubationinthICU.Accordingtotheflowrateinoxygentherapy,theyweredividedintogroupA(4lcases,4OL/min)and groupB(4Oases,O/in)eetofangtintcofortleveldicatosndeprogosiseompadee thetwogroupsResultsTerateofsecondintubationwiindaysandsuccsateofweangsowdnoatisticallysigniicantdieence between the two groups ( P>0.05 ).The scores for dry mouth and nasal cavity,and sore throat in group A were significantly lower than those in group B ( P<0.05 ).The arterial partial pressure of oxygen,arterial partial pressure of carbon dioxide and pH showed no statistically significant difference between the two groups( P>0.05 ).The incidence rates of adverse reactions in the two groups during oxygen therapy were close ( P>0.05 ).ThelengthofICUstay,lengthofhospital stayand theproportionof patientswithpoorprognosis during 28-dayfollow-up showed no statistically significant difference between the two groups( P>0.05 ).ConclusionHigh-flow nasal cannula oxygen therapy with aflowrateof/mincansigificantlyincreasecomfortlevelofelderlypatintswithseverepeumonia,witoutsignfcntifueneonthe success rate of weaning,blood gas indexes and short-term prognosis.

[Key words] Severe pneumonia;High-flow nasal cannula; Oxygen therapy flow rate;Success rate of weaning;Blood gas

重癥肺炎患者的肺部功能受到嚴(yán)重?fù)p害,容易出現(xiàn)呼吸功能不全,甚至呼吸衰竭,死亡率較高[]。(剩余9431字)

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