喹硫平聯(lián)合丙戊酸鎂治療男性雙相情感障礙的臨床療效及安全性評價

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【摘要】目的：探討聯(lián)合以喹硫平與丙戊酸鎂對雙相情感障礙男性患者施治的價值。方法：試驗對象選于2019年1月—2022年1月期間，在我院就醫(yī)的雙向情感障礙男性患者86例，以數(shù)字奇偶法均分為對照組與觀察組，在施治期間提供丙戊酸鎂與聯(lián)合喹硫平施治，統(tǒng)計組間癥狀改善情況與用藥反應(yīng)差異性。結(jié)果：觀察組狂躁癥狀及抑郁癥狀評分比對照組低（P

【關(guān)鍵詞】雙相情感障礙；男性；喹硫平；丙戊酸鎂；施治效果；不良反應(yīng)

Clinical efficacy and safety evaluation of quetiapine combined with magnesium valproate in the treatment of male bipolar disorder

WANG Juqin

Baiyin City， Gansu Province Huining County Tumen Xian Town health center， Baiyin， Gansu 730799， China

【Abstract】Objective： To explore the value of quetiapine combined with magnesium valproate in the treatment of male patients with bipolar disorder. Methods： The test subjects were selected from January 2019 to January 2022， 86 cases of male patients with bipolar disorder in our hospital were divided into control group and observation group by numerical even-odd method. Magnesium valproate and quetiapine combined treatment were provided during treatment， and the difference of symptom improvement and drug response between groups was statistically analyzed. Results： The scores of manic and depressive symptoms in the observation group were lower than those in the control group（P

【Key Words】Bipolar disorder； Men； Quetiapine flat； Magnesium valproate； Treatment effect； Adverse reactions

雙相情感障礙作為臨床常見精神疾病，具有較高發(fā)生率與復發(fā)率，在發(fā)病時患者主要交替存在抑郁與躁狂情緒，臨床癥狀以情緒低落、思維遲緩、意識行為衰退等為主，當其出現(xiàn)躁狂情緒時，易表現(xiàn)出心境高漲、活動增多及思維奔放等癥狀[1]。（剩余3332字）