基于“虛-滯-積"動(dòng)態(tài)演變探討糖尿病腎病的病機(jī)與治療

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[關(guān)鍵詞]糖尿病腎??；虛-滯-積；動(dòng)態(tài)演變；理論探討；辨證論治 [中圖分類號(hào)]R255.4 [文獻(xiàn)標(biāo)志碼]A [文章編號(hào)]doi：10.3969/j.issn.1674-070X.2025.06.019

Pathogenesis and treatment of diabetic nephropathy based on the dynamic evolution of "deficiency-stagnation-accumulation"

YANG Yuehua， LIN Yan*

FirstTeachingHospitalofTinjinUniversityofTraditionalChineseedicineNationalClinicalResearchCenterforCinee MedicineAcupunctureand Moxibustion，Tianjin 3oo382，China

[Abstract]Diabetic nephropathyisacommon complication ofdiabetes melitus and belongs to thecategoryof wasting and thirstdisordersinTCM.Chinesemedicinehasuniqueeficacyinthetreatmentofdiabeticnephropathynditisiportntto clarifythediseasemechanismtoguideclinicaltreatmentTepathogenesisofdiabeticnephropathyisoftencharacterizedasa combinationofdeficiencyattherootandexcessinthemanifestationThetransformationpatternof“deficiency-stagnationaccumulation”corespondstothepathologicalbasisofthisdiseaseprogressingfrodeficiencytoexcessDiabeticnepropathy mainlyinvolvesdeficincofspenandidney，leadingtodisorderedqisagnatinginthemeridiansandcollteralsichtu results inaccumulationofvariouspathologicalproductsanddamagetocollterals.Thesefactorsleadthediseaseintoitsterminal stage.Intermsoftreatmentthrapeuticstrategiesshouldbetilordtothunderlyingpathogenesiswithsagedinterventiostat appropriatelycombinethemethodssuchastonifyingthesplenand kidney，regulatingqi，clearingheatanddrainingdampnes， circulatingbloodandtransformingstasis，andremovingtoxinsandeliminatingturbidityThiscomprehensiveaproachaimsto provide the optimal treatment plan for diabetic nephropathy.

[Keywords]diabeticnephropathy；deficiency-stagnation-accumulation；dynamicevolution；theoreticaldiscussion；pattern dentification and treatment

糖尿病腎病是糖尿病最常見的微血管并發(fā)癥之一，其特征是蛋白尿、進(jìn)行性腎功能損害及腎臟纖維化，最終進(jìn)展至終末期腎病。（剩余10222字）