牙頜干細(xì)胞與免疫細(xì)胞的交互調(diào)控作用

打開文本圖片集

[中圖分類號(hào)]Q26 [文獻(xiàn)標(biāo)志碼]A[doi] 10.7518/gjkq.2025050

[Abstract]Dental stemcellsareeasytoobtain with few technicaland ethicalconstraintsandhave strong proliferative abilityandstablemorphology.Immunecelsarewidelydistributed inthebodyandcanregulatedentalstemcels，which is beneficialforthetreatmentof tissehomeostasisandinflammatorydiseases.Furtherresearchontheirmutualregulato ry mechanisms has important clinical significance.The interactionbetweendental stemcelsand immunecells cancontrolthe biologicalbehaviorofdentalstemcels，regulatethelocalinflammatorymicroenvironment，andpromotetissuere generation and inflammation treatment. However，the mechanism underlying the interaction regulation between dental stemcellsandimmunecelsislargelyunclear，andthediscoveredmechanismslackclinicalexperimentalevidence.Further exploration is needed before appying thesecells to clinical treatment.Thisarticlesummarizes the mutual regulatory efctsand mechanisms betweendental stemcelsand immunecells to providereference fortheirclinical applications. [Key words] mesenchymal stemcell；stomatognathic system；immunecell；immunoregulation；tissueregeneration

間充質(zhì)干細(xì)胞是具有自我更新和多向分化潛能的一群異質(zhì)性祖細(xì)胞，與免疫細(xì)胞之間相互作用非常廣泛，其通過造血產(chǎn)生免疫細(xì)胞，在再生等過程中兩者產(chǎn)生相互作用。（剩余22896字）