淋巴管超聲造影與靜脈超聲造影在鑒別診斷甲狀腺癌頸部轉(zhuǎn)移淋巴結(jié)中的應(yīng)用
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中圖分類號(hào)：R44.451 文獻(xiàn)標(biāo)識(shí)碼：A 文章編號(hào)：1000-503X（2025）01-0016-07
DOI：10.3881/j.issn.1000-503X.16120
Lymphatic and Venous Contrast-Enhanced Ultrasound Imaging for Differential Diagnosis of Cervical Lymph Node Metastasis in Thyroid Cancer
LI Xu，WAN Wenbo，GAO Tian，GOU Taohua，ZHANG Yan
Department of Ultrasound，The First Medical Center，Chinese PLA General Hospital，Beijing 100853，China
Corresponding author：ZHANG Yan Tel：010-66935241，E-mail：zhangyaner301@126.com
ABSTRACT： ObjectiveTo investigate the value of the novel lymphatic contrast- enhanced ultrasound （LCEUS）and conventional venous contrast-enhancedultrasound（VCEUS）in the diferential diagnosisof benign and malignant cervical lymph nodes in patients with thyroid cancer.MethodsPatients with suspected thyroid cancer underwent conventional ultrasound，VCEUS，and LCEUS examinations of cervical lymph nodes before biopsy.The diagnosticabilities of conventional ultrasound，VCEUS，and LCEUS were compared with pathological results as the golden standard. ResultsForty-four patients with 52 lymph nodes were included in the final data.Thirty-eight metastatic lymph nodes were confirmed bypathological results，and14 were benign.The diagnostic sensitivity，specificity，and accuracy were 97.37% ， 71.43% ，and 90.38% for LCEUS， 92.11% ， （20 35.71% ，and 76.92% for VCEUS，and 94.74% ， 21.43% ，and 75.00% for conventional ultrasound， respectively.The area under the curve of LCEUS analyzed bythe receiver operating characteristic curve was greaterthanthatofVCEUS（ P=0.020 ）and conventional ultrasound（ P<0.001 ）.ConclusionLCEUS could significantly improvethe diferential diagnosis of cervical lymph node metastasis in the patients with thyroid cancer，providing a basis for precise clinical treatment.
Key words：thyroid；ultrasound；contrast-enhanced ultrasound imaging；lymph node
ActaAcadMedSin，2025，47（1）：16-22
甲狀腺癌發(fā)病率居高不下，已引發(fā)全球關(guān)注，盡管大多數(shù)病例為預(yù)后較好的乳頭狀癌，但仍有 60% ＼～70% 的機(jī)率發(fā)生頸部淋巴結(jié)轉(zhuǎn)移[1]。（剩余11031字）