Zn,AI-CDs對(duì)四環(huán)素類抗生素的超靈敏熒光檢測(cè)
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中圖法分類號(hào)：0652.7 文獻(xiàn)標(biāo)識(shí)碼：A 文章編號(hào)：1000-2324（2025）03-0444-08
Abstract：Tetracycline antibiotics（TCs）are widelyused in medicineand aquaculture.Theirresidues poseathreat to food safetyand theecologicalenvironment.Therefore，itiscrucialtodevelopeficientandsensitive detectionmethods forTCs. This study utilizes sodium citrate as the carbon source， incorporates Zn and Al doping，and synthesizes carbon dots （Zn， AlCDs）through a hydrothermal method.By employing these carbon dots as fluorescent probes，ultrasensitive fluorescence detectionofTCisachieved. WiththeincreaseofTCsconcentration，the detectionsystemexhibitsgreen fluorescene，anda good linear connectionisobserved betwen fluorescence intensityandTCs concentration.The detection system has linear ranges of 0.01～7μM ， 0.01～7μM 0.01～5μM ，and 0.01～7μM fortetracycline hydrochloride （TCH），chlortetracycline hydrochloride（CTC），oxytetracycline hydrochloride（OTC），anddoxycyclinehydrochloride（DOC），respectively，with detection limits of 5.6nM ，7.41 nM， 4.28nM and 13.5nM ，respectively.Different types of tetracyclines are distinguished by the emisson wavelengthof thesystemic fluorescence.Inaddition，the Zn，Al-CDs material issuccessfullyappliedto detectTCH intapwater，river waterand milk，and the paper-based sensor prepared with Zn，Al-CDscanachieve semiquantitativevisualdetectionofTCs，ndicatingthematerial'spotentialasaqualitativeandquantitativedetectionssorfor tetracycline antibiotics.
Keywords：Tetracyclines;carbondots;detection;fluorescence
TCs作為一類廣譜抗生素，由于其優(yōu)異的抗菌性和低廉的成本，已被廣泛用應(yīng)于農(nóng)業(yè)養(yǎng)殖業(yè)，用于預(yù)防和治療疾病。（剩余10292字）