孕晚期陰道微生態(tài)失調對新生兒敗血癥的影響

打開文本圖片集

Abstract  Objective：To analyze the correlation between vaginal microecology disorder in the third trimester and neonatal septicemia，so as to provide a reference for better prevention and treatment of neonatal septicemia.Methods：A total of 128 mothers of neonates with neonatal septicemia admitted to a tertiary grade A hospital from September 2019 to September 2021 were selected as the case group，and 128 mothers of healthy neonates hospitalized in the same period were randomly selected as the control group.The vaginal microecology of the two groups in the third trimester was detected，the correlation between vaginal microecology disorder in the third trimester and neonatal septicemia was analyzed，and the evaluation value of vaginal microecology index on the risk of neonatal sepsis was tested.Results：The rate of vaginal microecological disorder in the case group（89.1%） was higher than that in the control group（79.7%），the positive rate of candida in case group（7.8%） was higher than that in control group（2.3%），the positive rate of G?bacilli（95.3%） was lower than that of the control group（100.0%），and the difference was statistically significant（P<0.05）.Logistic regression analysis results showed that candida positivity in the third trimester was associated with neonatal sepsis（OR=3.721，P=0.045）.Kendall correlation analysis showed that they were positively correlated（r=0.125，P=0.047）.The ROC showed that the AUC of Candida positivity in the third trimester was 0.527 for the assessment of neonatal sepsis.Conclusion：Clinical attention should be paid to vaginal microecological disorder in the third trimester to prevent and reduce the occurrence of neonatal sepsis.

Keywords  third trimester； vaginal microecology； neonates； septicemia； ROC； influencing factors； nursing

摘要  目的：分析孕晚期陰道微生態(tài)失調與新生兒敗血癥的相關性，為更好地防治新生兒敗血癥提供參考依據(jù)。（剩余6939字）