脊髓損傷型胸腰椎骨折病人術(shù)后早期發(fā)生低氧血癥預(yù)測模型的建立

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Abstract  Objective：To construct a early warning model to investigate the risk factors of early postoperative hypoxemia in patients with spinal cord injury?type thoracolumbar fractures.Methods：A total of 151 patients with thoracolumbar fractures admitted to our hospital from May 2017 to March 2021 were selected as the research subjects.The clinical data of the patients were collected.The univariate analysis and Logistic regression were used to analyze early postoperative hypoxemia risk factors in patients with spinal cord injury?type thoracolumbar fractures.A nomogram prediction model was established accordingly.Results：Hypoxemia occurred in 32 patients 1 hour after the operation，and the incidence rate was 21.19%.Logistic regression analysis showed that higher body mass index （BMI），hypertension，diabetes，higher American Spinal Injury Association（ASIA） classification，and postoperative hypothermia were independent risk factors for early postoperative hypoxemia in patients with spinal cord injury?type thoracolumbar fractures（P<0.05）.A nomogram risk model for predicting early postoperative hypoxemia in patients with spinal cord injury?type thoracolumbar fractures was established.It has been verified to have good predictive ability.The concordance index（C?index） was 0.806，the calibration curve was close to the ideal curve，and the lower area of the receiver operating curve（ROC） was 0.814，95%CI（0.772，0.854），within the range of 8% to 82%.The nomogram predicted a higher net benefit value.Conclusions：Higher BMI，hypertension，diabetes，higher ASIA classification，and postoperative hypothermia are risk factors of early postoperative hypoxemia in patients with spinal cord injury?type thoracolumbar fractures.The constructed Nomogram model could effectively predict the risk of incident of postoperative early hypoxemia，which has a certain clinical value.

Keywords  spinal cord injury； thoracolumbar fractures； hypoxemia； risk factors； Nomogram

摘要  目的：探討脊髓損傷型胸腰椎骨折病人術(shù)后早期發(fā)生低氧血癥的危險因素，構(gòu)建護(hù)理預(yù)警模型。（剩余10128字）