安寧療護(hù)理念下破解終末期患者參與臨床試驗(yàn)困境的建議

[關(guān)鍵詞]安寧療護(hù)；終末期受試者；臨床試驗(yàn)

[中圖分類號(hào)]R-052 [文獻(xiàn)標(biāo)志碼]A [文章編號(hào)]1001-8565（2025）07-0924-05

DOI：10.12026/j. issn.1001-8565.2025.07.17

Abstract： Palliative care is recognized as an effctive measure to improve the quality of life for patients with end-stage diseases，and the significance and role of such patients participating in clinical trials to conquer major diseases has also become a broad consensus.However，due to the special physical，psychological，and social conditions of terminal trial participants，the ethical problems encountered in the trial processare more serious and complex. Drawing on ethical practice experience，these seemingly common phenomena and issues were deeply analyzed. Combined with the palliative care philosophy for end-stage patients，this paper proposed a series of improvement suggestions throughout the entire life cycle of clinical trials，hoping to promote the quality improvement of clinical research in which end-stage patients participateas subjects，while effectively protecting the safety and rights of the subjects and ensuring they receive appropriate palliative care during their participation in clinical trialsorclinical-related scientific research.

Keywords： palliative care;end-stage patients；clinical trials

盡管人類壽命在不斷延長(zhǎng)，但是生病甚至病故幾乎是每個(gè)人都無法避免的自然現(xiàn)象，既要通過醫(yī)學(xué)科學(xué)研究努力攻克不治之癥，又要實(shí)現(xiàn)人類在不治之癥面前能夠有尊嚴(yán)地度過生命的最后時(shí)光。（剩余7326字）