血液非靶向代謝組學在研究脊髓損傷后膀胱功能改變的可行性分析

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【中圖分類號】R3【文獻標志碼】A【收稿日期】2025-01-22

Feasibility of blood untargeted metabolomics in studying bladder function changes after spinal cord injury

Kang Yinbo，Shuang Weibing （Department of Urology，The First Hospital of Shanxi Medical University）

【AbstractTraumaticspinalcordinjuryandbladderinjuryarebothcommonsurgicalinjuries.Metabolomicssudiesarethequalitative andquantitativeanalysisofallmetabolitesinaspecificpartoftheorgaismandthescienceoftechanginglawsofthesemtaboits underexternalinfluencsordseaseconditions.Thetechnologyismailytoanalyzthemetabolitesinbodyfuids，els，ndissus， andhasbecomeoneof theimportantmeansfordiscoveringbiomarkers.Thepsyhopathologyofspinalcordinjuryisverycomplex. Bloodmetabolomicsalowsdiferentialanalysisofthesubstancesinblodandhasgreatvalueforexploringthediseaseproesand mechanism.

【Keywords】blood metabolomics;spinal cord injury;bladder injury;biomarkers

脊髓損傷（spinalcord injury，SCI），是由于創(chuàng)傷或非創(chuàng)傷因素導致脊髓受損，引發(fā)結(jié)構(gòu)或功能上的損害，是中樞神經(jīng)系統(tǒng)中的1種嚴重疾病。（剩余15491字）