原發(fā)性腦腫瘤病人癥狀群現(xiàn)狀及其影響因素

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Current situation and influencing factors of symptom cluster in patients with primary brain tumor

PAN Huaying，LUO Lingling，REN Jiali，ZHANG Zhou，SU Li，ZHAO Huiming，XIA Haoran，CHEN Ting，WANG YaliAffiliated Hospital of North Sichuan Medical College，Sichuan 637000 ChinaCorresponding Author WANG Yali，E-mail：ya_liwang@163.com

Abstract Objective：To investigate the symptoms of patients with primary brain tumor （PBT）， and to explore the types of symptom clusters and the factors affecting them.Methods：A total of 257 PBT patients who attended a comprehensive tertiary hospital in Sichuan Province from March to November 2022 were selected for the study. The questionnaire survey was conducted by using the general information questionnaire and the Chinese version of the Anderson Brain Tumor Symptom Assessment Scale;the symptom clusters were extracted by using the exploratory factor analysis method， and the influencing factors of the symptom clusters were analyzed by using the multivariate linear regression analysis method.Results：Five symptom clusters were finally identified in this study， including neurocognitive symptom cluster， decreased energy mood symptom cluster， gastrointestinal symptom cluster， pain symptom cluster， and appearance elimination symptom cluster， and the cumulative variance contribution rate was 73.856%. The results of multifactorial analysis showed that occupation， annual per capita household income， burden of medical treatment， tumor type， tumor location， whether or not the tumor was combined with chronic diseases， disease duration， and Kasperger′s functional status （KPS） score were the factors influencing the severity of different symptom clusters （P<0.05）.Conclusion：Patients with PBT have a high symptom burden， with the most prominent of the five symptom clusters being the energy-reducing mood cluster. Patient characteristics that should be emphasized by healthcare professionals include workers/individuals/freelancers， low per capita annual family income， high healthcare burden， chronic diseases， long duration of illness， KPS score ≤70， colloid tumors and pituitary tumors， especially those symptom clusters that are influenced by different factors.

Keywords primary brain tumors;symptom;symptom clusters;influencing factors；nursing

摘要 目的：調(diào)查原發(fā)性腦腫瘤（PBT）病人的疾病癥狀，分析其癥狀群類(lèi)型及影響因素。（剩余10328字）