紫杉醇復(fù)合順鉑同步放療盆腔淋巴結(jié)陽(yáng)性Ⅲ期宮頸癌的療效

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摘 要 目的:探討紫杉醇復(fù)合順鉑同步放療盆腔淋巴結(jié)陽(yáng)性Ⅲ期宮頸癌的治療效果。方法:將80例盆腔淋巴結(jié)陽(yáng)性Ⅲ期宮頸癌患者隨機(jī)分入對(duì)照組和觀察組各40例。對(duì)照組予以順鉑同步放療治療,觀察組予以紫杉醇復(fù)合順鉑同步放療治療。觀察兩組患者的臨床療效以及發(fā)生的不良反應(yīng)情況。結(jié)果:觀察組患者的臨床療效,不良反應(yīng)發(fā)生率,隨訪3年的生存、復(fù)發(fā)、轉(zhuǎn)移情況優(yōu)于對(duì)照組(均P
關(guān)鍵詞 紫杉醇 順鉑 放療 盆腔淋巴結(jié)陽(yáng)性Ⅲ期宮頸癌 治療效果
中圖分類號(hào):R979.19; R737.33 文獻(xiàn)標(biāo)志碼:B 文章編號(hào):1006-1533(2022)07-0020-02
引用本文 梁業(yè), 陳勇, 劉小蘭. 紫杉醇復(fù)合順鉑同步放療盆腔淋巴結(jié)陽(yáng)性Ⅲ期宮頸癌的療效[J]. 上海醫(yī)藥, 2022, 43(7): 20-21; 71.
Efficacy of paclitaxel combined with cisplatin in concurrent radiotherapy for pelvic lymph node-positive stage Ⅲ cervical cancer
LIANG Ye, CHEN Yong, LIU Xiaolan
(Department of Oncology, Xin’gang Central Hospital, Xinyu 338000, China)
ABSTRACT Objective: To explore the effect of concurrent radiotherapy with paclitaxel and cisplatin for pelvic lymph node-positive stageⅢ cervical cancer. Methods: Eighty patients with pelvic lymph node-positive stageⅢ cervical cancer were randomly divided into a control group and an observation group with 40 cases each. The control group was treated with concurrent cisplatin radiotherapy while the observation group was treated with paclitaxel combined with cisplatin concurrent radiotherapy. The clinical efficacy and adverse reactions in the two groups were observed. Results: The clinical efficacy, incidence of adverse reactions, survival, recurrence, and metastasis at 3 years of follow-up were better in the observation group than the control group(all P
KEy wORDS paclitaxel; cisplatin; radiotherapy; pelvic lymph node-positive stageⅢcervical cancer; therapeutic effect
宮頸癌屬于臨床常見的婦科惡性腫瘤,患者初期一般無(wú)明顯臨床癥狀,隨著疾病的進(jìn)展,可表現(xiàn)為陰道異常出血、接觸性出血等,而在疾病晚期,腫瘤會(huì)侵犯宮頸周圍組織或器官,則會(huì)出現(xiàn)肛門墜脹感、腿部腫脹、腎功能損傷、陰道大出血等臨床現(xiàn)象,嚴(yán)重威脅著患者的生命安全[1]。(剩余2856字)