雷火灸聯合中藥治療對凍融胚胎移植妊娠結局的影響

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關鍵詞：雷火灸；子宮內膜容受性；凍融胚胎移植；臨床妊娠率

中圖分類號：R715文獻標志碼：A 文章編號：1001-5779（2025）05-0448-05

DOI：10.3969/j.issn.1001-5779.2025.05.006

Abstract：Objective：To explore theeffectofThunder-fire Moxibustioncombinedwith Chinese medicineon the assisted reproductiveoutcomes of patientsundergoing frozen-thawed embryo transfer.Methods：Aretrospective analysis was conductedontheclinicaldataof8O infertilepatientswhounderwentfrozen-thawedembryo transfertreatment inthe Departmentof Reproductive Medicine at Xinyu Maternal and Child Health Hospital from January2O2Oto December 2023.The patients were divided into two groups based on the treatmentreceived： the experimental group（40cases）and the control group （40 cases）.The control groupunderwent endometrial preparationusing a hormone replacement regimen， whiletheexperimentalgroupreceivedThunder-fireMoxibustioncombinedwithidney-tonifyingChinesemedicinereatment onthebasisofhormonereplacementtherapy.Thegeneralcharacteristicsofthepatients，endometrial thickness ontheday of embryo transfer，and pregnancyoutcomes were analyzed between the two groups.Results：There were no statistically significantdiffrences inheaverageage，infertilityduration，bodymassindex，andbasalhormonelevelsofthepatients and their spouses between the two groups （ P>0.05 ）.Similarly，there were no statistically significant differences in the quality and number of transplanted embryos （ P>0.05 ）. The endometrial thickness in the experimental group on the day of transplantationwassignificantlyincreasedcomparedwiththecontrol group，withastatisticallsignificantdiference 1 （P=0.003） . The embryo implantation rate 65.9% ）and clinical pregnancy rate（ 70% ） in the experimental group were both higher than those in the control group，with embryo implantation rate （42.5% ）and clinical pregnancy rate （47.5%） ，and thedifferenceswere statistically significant（ P<0.05， .Thebiochemical pregnancy ratein theexperimental group（ 5% ）was much lower than that in the control group（ 20% ），withastatisticallysignificantdifference（ P<0.05 ） Conclusion：The treatmentofThunder-fire Moxibustioncombinedwith kidney-tonifying traditionalChinesemedicinecan increaseendometrial thickness，improveendometrial morphology，therebyenhancing endometrialreceptivity，and improvingthe embryo implantationrateand clinical pregnancyrate in patients undergoing frozen embryo transfer. KeyWords：Thunder-fire Moxibustion;Endometrialreceptivity；Frozen-thawedembryotansfer;Clinicalpregnancyrate

當前不孕不育的發(fā)病率逐年上升，據世界衛(wèi)生組織統(tǒng)計，在歐美發(fā)達國家，每6對夫婦中就有1對夫婦面臨不孕不育的困擾[1，而輔助生殖技術已成為解決不孕不育問題的主要途徑。（剩余7072字）