不同年齡段食蟹猴血生化指標(biāo)檢測及相關(guān)性分析

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關(guān)鍵詞食蟹猴;血液生化指標(biāo);年齡段;相關(guān)性中圖分類號Q95-33文獻(xiàn)標(biāo)識碼A文章編號 0517-6611(2025)13-0071-04doi:10.3969/j.issn.0517-6611. 2025. 13. 014
開放科學(xué)(資源服務(wù))標(biāo)識碼(OSID):
Detection and Correlation Analysis of Blood Biochemical Across Different Age Groups of Cynomolgus Monkeys PANXi-ying1,ZHANG Pengfei,SHENGuoetal(1.Guangxi HuarenJiying BiotechnologyCo.,Ld.,Naning,Guangxi500; 2.Guangxi Academy of Sciences,Nanning,Guangxi 530007)
AbstractObective]Tostudythebloodbiochemicalofcynomogusmonkeysatdiferentagegroupsndivestigatetherelatioshpbetweenthetwovariables.Method]Atotalof196malecynomolgusmonkeys were selectedanddividedinto5groups:juvenilegroup(1-4 yearsold),younggroup(5-8yearsold),midle-agegroup(9-12yearsold),oldgroup(13-16yearsold)andveryoldgroup(17-20 yearsold)19lodceicalparameterseredetectedompasosereadeaongdierentagegoupsndthelatioieteen each parameterandagewasanalyzed.Result]HBAlc,F(xiàn)BGandTGincreasedwithageandwere positivelycorelatedwithage.BUNand CREwerenegatielycelatedwithagefromjuenile toyoung,andpositvelyorrlatedwithagefromyoungtveryoldCHL,LDL-C, HDL-C,ALB,,ASGG,ALP,Caandwrenegtivelyoelated withgfrojuveniletomdlegendpositivelyae withagefromdlaeteryold,ndCKweegativeloeadijueilyoungndosiee tedwithagefromyoungtoveryold.Conclusion]isstudyprovidedareferencebasisforteapplicationofcyomolgusmokeysfeld of biomedicine.
Key WordsCynomolgus monkeys;Blood biochemical; Age group;Correlation
動物實驗在人類疾病機理研究和新藥研發(fā)過程中是不可缺少的一部分,非人靈長類實驗動物與人類的遺傳物質(zhì)具有 57.0%~98.5% 的同源性,是新藥研發(fā)臨床前最理想的實驗動物。(剩余6252字)