(P=0.982</sub> )。發(fā)熱疾病組內(nèi) NE%.LY% 、 MO% 、NLR、MLR、SII均是急性上呼吸道感染的單危險(xiǎn)因素。ROC曲線分析顯示各單危險(xiǎn)因素和構(gòu)建的列線圖模型均可有效篩查急性上呼吸道感染,對(duì)應(yīng)的曲線下面積(AUC)為0.615\~0.859,其中列線圖模型最高(0.859),其對(duì)應(yīng)的靈敏度和陰性預(yù)測值最高,分別為 87.50% 和 77.78% 。 MO% 對(duì)應(yīng)的特異度和陽性預(yù)測值最高,分別為 75.00% 和 83.84% 。結(jié)論外周血白細(xì)胞分類及相關(guān)炎癥指標(biāo)可有效鑒別上呼吸道感染和其他發(fā)熱疾病。該研究基于外周血白細(xì)胞分類及相關(guān)炎癥指標(biāo)構(gòu)建的列線圖模型,可為本區(qū)縣臨床醫(yī)生鑒別發(fā)熱患者的病因提供參考。-龍?jiān)雌诳W(wǎng)" />

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急性上呼吸道感染與其他發(fā)熱疾病患者外周血白細(xì)胞及相關(guān)炎癥指標(biāo)特征分析

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LinFangmi',HuangJian2,ChenHuojil 'DepartmentofClinicalLaboratory,ShaxianDistrictGeneral HospitalofSanmingCitySanming365o5o,China; 2DepartmentoflinicalLaboratory,the90othHospitalofJointLgistics SupportForce,F(xiàn)uzhou 35oooo,China

【Abstract】 Objective Study the diagnostic value of peripheral blood leukocyte classification and related inflammatoryindicators in distinguishingacute upperrespiratory infections fromotherfebrile diseases,andcombine multiple indicators to constructa predictivemodel.MethodsAretrospective analysis was conductedon theblood routine results of 165 patients with'fever within three days'as the main complaint who visited Shaxian District General Hospital in Sanming City from January 2O23 to December 2O24.According to the causes of fever,fever patients were divided into acute upper respiratory infection group of 1OO cases and other fever disease group of 65 cases.And 1OO healthy individuals during the same period were selectedas the control group.Compare the differences in peripheral blood leukocyteclasificationand related inflammatory indicatorsbetweenthe fever disease group and the control group,acute upper respiratory infection group and other fever disease groups, including neutrophil percentage (NE % ), lymphocyte percentage (LY % ),monocyte percentage ( MO% ), neutrophil to lymphocyteratio (NLR),monocyte to lymphocyteratio (MLR),systemic inflammatoryresponse index (SIRI),and systemic immune inflammatory index (SI).Logisticbinaryregressionanalysis of risk factors foracuteupper respiratory infectionsandconstruction of a nomogram model.ROC analysis evaluation of various risk factors and the nomogram model for screening the diagnostic efficacy of acute upper respiratory infections.ResultsThe levels of LY % ,MO % ,and MLR in the acute upper respiratory infection group were significantly higher than those in other feverdisease groups( P =0.002,

【Key words】 Respiratory tract infections;Leukocytes; Inflammatory cell; Systemic inflammatory responseindex;Systemic immune inflammationindexDOI:10.19522/j.cnki.1671-5098.2025.05.005

急性上呼吸道感染是一種炎癥性疾病,可有急性發(fā)熱、咳嗽、鼻塞流涕等典型的臨床表現(xiàn)1。(剩余7464字)

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