微生物-腸-心軸”與心血管疾病相關(guān)性的研究進(jìn)展

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中圖分類號：R54 文獻(xiàn)標(biāo)志碼：A DOI：10.3969/j.issn.1007-7146.2025.03.003

Abstract：Cardiovasculardisease iscurrentlytheleadingcauseofdeath inthe world，andalthoughgreatprogresshas been made ntheresearchandclinicaltreatmentofitspathogenesis，themortalityrateisstillhigh，andnew waysofscientific interventionareurgentlyneeded.Intestinalflora is the most numerous andcomplex microbialcommunity in the humanbody， whichplaysanimportantroleinthealthyomeostasisofthebodyanditsimbalancecanleadtoavarietyofchonicdiseases includingcardiovasculardisease，andforma“microbiome-gut-heartaxis”relationship，whichspeculates thatintestinalflora anditsmetabolitesmaybepotentialbiologicaltargetsforthe treatmentofcardiovasculardisease.Thisarticlefocusesonthe regulatorymechanismbetween the“microbiome-gut-heartaxis”andcardiovasculardisease，andproposes the preventionand treatmentofcardiovasculardiseases fromtheperspectiveofintestinalmicrobiota，inorder toprovidereferenceforclinical treatment.

Keywords：gutmicrobes;cardiovasculardiseases;microbiome-gut-heartaxis;intestialflora metabolites;novelcoroavirus （ActaLaser Biology Sinica，2025，34（3）：214-220）

心血管疾?。╟ardiovasculardisease，CVD）是一種高發(fā)病率、高致殘率、高死亡率及高復(fù)發(fā)率的疾病，是導(dǎo)致我國居民死亡的主要原因。（剩余15093字）