短鏈脂肪酸對(duì)腸道動(dòng)力的作用及其機(jī)制研究進(jìn)展

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Research ProgressonRolesand MechanismsofShort-chainFattyAcids in IntestinalMotilityCHENQiJIANG Ya，JIANGuqinDeprtmentofGstronterologherstfiatedHositalfjingdicalUivesityng （210029）

Correspondence to： JIANG Liuqin， Email： jiangliuqin@163.com

AbstractShort-chain fattyacids （SCFAs）aremetabolitesof intestinal microbiota produced from dietary fiber fermentation.Theyregulate theintestinal motilitythrough multiplemechansmsincluding modulationof gastrointestinal hormones，enteric nervoussystem，smoothmusclecelsandinterstitialcellsofCajal（ICC）.AlerationsinSCFAsoceation have beenobserved in patients with intestinal motilitydisorders.Therapeutic interventions such as SCFAssupplementation， high-fiberdiets，probiotics/prebiotics，and fecal microbiota transplantation （FMT）havedemonstratedeficacyinimproving clinicalsymptoms.This articlereviewed research progressontheroles and mechanisms ofSCFAs in intestinalmotility.

KeyWordsShort-Chain FattyAcids;Gastrointestinal Motility；Intestinal Microbiota

腸道動(dòng)力對(duì)營(yíng)養(yǎng)物質(zhì)的消化和吸收至關(guān)重要，但容易受多種因素的影響，包括免疫應(yīng)答、腸神經(jīng)系統(tǒng)、膽汁酸代謝、黏液分泌、腸道微生物群等。（剩余14820字）