氧化應(yīng)激與炎癥性腸病

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Oxidative StressandInflammatory BowelDiseaseLI Hanyu’，SHDongyun2，ZHENGSongbai'.'Departmentof GastroenterologyHudongHositalfliatedtdnUesitynghai（o）;eprtmentofhestrd Moleculariology，SchoolofasicedicalSciences，F(xiàn)udanUniversity，hnghai

Correspondence to：ZHENG Songbai，Email： songbai10o9@163.com

AbstractInflammatory bowel disease （IBD），agroupof chronic non-specific gastrointestinal inflammatorydisorders， hasshownanupward trend inglobal incidence.However，thepathogenesisofIBDremains elusive，andthetherapeutic effctsarefrequentlyfarfromsatisfactory，significantlycompromising thequalityof lifeof patients.Inrecentyears， research onthe association between oxidative stressandIBD has drawn substantial atention，which mayunveil novel therapeutic targets for IBD.This article reviewed the relationship between oxidative stress and IBD.

KeyWordsInflammatory Bowel Disease;CrohnDisease；Colitis，Ulcerative;Oxidative Stress

炎癥性腸?。╥nflammatoryboweldisease，IBD）是一組慢性非特異性胃腸道炎性疾病，包括潰瘍性結(jié)腸炎（ulcerativecolitis，UC）和克羅恩?。–rohn'sdisease，CD），其臨床表現(xiàn)除腹痛、腹瀉、便血等腸道癥狀外，還有發(fā)熱、疲乏等全身表現(xiàn)以及關(guān)節(jié)、皮膚、黏膜、肝膽等腸外損害。（剩余20071字）