長骨釉質(zhì)瘤合并骨巨細(xì)胞瘤1例并文獻(xiàn)復(fù)習(xí)

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Adamantinoma of long bones combined with giant cell tumor of bone： a case reportand literature review

ZHU Yali1， FAN Meng2，WU Juan1'， YANG Guifang1

1.Department of Pathology， Zhongnan Hospitalof Wuhan University，Wuhan 430o71，China

2. Department of Pathology，Wuxue Second People's Hospital，Huanggang 43540o，Hubei Province，

China

3.DepartmentofPathology，Zaoyang FirstPeople's Hospital， Xiangyang 4412oo，Hubei Province， China

Corresponding author： YANG Guifang， Email： YangGF@whu.edu.cn

【Abstract】 Adamantinoma of long bone （AD） and giant cell tumor of bone （GCTB） typically present as solitary bone lesions. It is extremely rare for both types of tumors to occur simultaneously inone patient.This article reports a17-year-old female patient who was admitted to the hospital due to right knee pain. Imagery suggested that the lower of the right femur and the upper of the right tibia had undergone bone destruction with the formation of soft tissue shadows. The clinicians diagnosed bone tumors and perform tumor curettage.The postoperative pathological diagnosis of the right femur lesion was GCTB，and the right tibia lesion was AD.The postoperative recovery was favorable，and no recurrence or metastasis so far. In this paper， we review the relevant literatures and summarize the clinical manifestations，imaging characteristics，pathomorphological features，andtreatmentmodalitiesofGCTBandAD.

【Keywords】Adamantinoma of long bones； Giant cell tumor of bone； Pathologic diagnosis； Bone tumors

長骨釉質(zhì)瘤是一種罕見的具有上皮和間葉雙相分化的骨腫瘤，好發(fā)于長骨{]。（剩余13020字）