65% ；HFsnEF患者老年人、女性的比例更高，腦鈉肽值更低，左心室更小，瓣膜疾病、心律失常和高血壓性心臟病是主要的心力衰竭病因；HFsnEF和死亡率之間的關(guān)系具有性別依賴性，可能由于老年女性好發(fā)冠狀動(dòng)脈微血管障礙，加之心臟體積小、交感神經(jīng)興奮性高，使其更有可能發(fā)生心血管事件。目前對(duì)于HFsnEF的診斷和治療仍沿用射血分?jǐn)?shù)保留的心力衰竭的方法。本文通過梳理文獻(xiàn)，系統(tǒng)地探討了HFsnEF的研究進(jìn)展，以期為HFsnEF的深入研究提供借鑒。-龍?jiān)雌诳W(wǎng)" />

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射血分?jǐn)?shù)超常的心力衰竭的研究進(jìn)展

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【中圖分類號(hào)】R541.62【文獻(xiàn)標(biāo)識(shí)碼】A DOI：10.12114/j.issn.1007-9572.2024.0307

【Abstract】More and more studies have proved that heart failure with supra-normal ejection fraction（HFsnEF） isanewheartfailurephenotypewithdiferentcharacteristics，butitsstudyisstillintheexploratorystageathomeandbroad Thecriticalvalueofsupernomaljectionfraction（snLVEF）isstllontroversial，butmoststudiesdefineitasleftvtricular ejection fraction>65 % ；the proportion of elderly and female patientswith HFsnEFis higher，with lower natriuretic peptide valuesandsmalerleftventricles，andvalvulardisease，arhthmia，andhypertensiveheartdiseasearethemaincausesofheart failure；andtherelationshipbetween HFsnEFandmortalityhasagender-dependentnature，posiblyduetotheprevalenceof coronarymicrovasculardisorders inelderlywomen，coupledwithsmallheartsizeandhighsympatheticexcitability，making them morelikelytosuffercardiovascularevents；thecurrentdiagnosisandtreatmentofHFsnEFstllfollowstheHFpEFapproachBy combingtheliterature，thispapersystematicallydiscusss theresearchprogressofHFsnEF，withaviewtoprovidingaeference for the in-depth study of HFsnEF.

【Key Words】Heartfailure；Heartfailure with supra-normal ejectionfraction；Ejectionfraction；Sympathetic nervous system；Review

心力衰竭是不同病因引起的一組臨床綜合征，其病理生理機(jī)制存在差異，包含3個(gè)要素：（1）心臟結(jié)構(gòu)和/或功能異常；（2）心力衰竭的癥狀和/或體征；（3）腦鈉肽水平升高和/或肺部或全身瘀血的客觀證據(jù)。（剩余13964字）

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