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植物可變剪接研究進展

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摘要:選擇性剪接廣泛存在于植物中,是生物體轉(zhuǎn)錄組和蛋白質(zhì)組多樣性的主要來源。隨著科技的發(fā)展,可變剪接的研究方法逐漸變得簡單方便高效,越來越多的可變剪接事件在植物中被發(fā)現(xiàn)。本研究對植物可變剪接的機制、研究方法以及幾種植物的最新可變剪接研究進展進行分析,并且對未來應(yīng)深入研究的方向給出了建議。

關(guān)鍵詞:mRNA;可變剪接;植物;擬南芥;大豆;單分子測序技術(shù)

中圖分類號:S1文獻標(biāo)志碼:A論文編號:cjas2020-0190

Research Progress of Alternative Splicing in Plants

XU Yue1,2,3,4, WANG Xi1,2,3, SHEN Zimeng1,2,3,5

(1College of Advanced Agriculture and Ecological Environment of Heilongjiang University/ Sugar Beet Research Institute of Chinese Academy of Agricultural Sciences, Harbin 150080, Heilongjiang, China; 2The Key Laboratory of Sugar Beet Genetic Breeding, Colleges of Heilongjiang Province/ Sugar Beet Engineering Research Center of Heilongjiang Province, Harbin 150080, Heilongjiang, China; 3National Sugar Crops Improvement Center/Key Laboratory of North Sugar Crop Resource and Utilization, Chinese Academy of Agricultural Sciences, Harbin 150080, Heilongjiang, China; 4Shanghai Belief Biomed Pharmaceutical Technology Co., Ltd., Shanghai 200000, China; 5China Blue Sky Ecological Technology (Beijing) Co., Ltd., Beijing 100083, China)

Abstract: Alternative splicing is widespread in plants and is the main source of transcriptome and proteome diversity in organisms. With the development of science and technology, the research methods of alternative splicing have gradually become simple, convenient and efficient, and more and more alternative splicing events have been discovered in plants. The article mainly introduces the mechanism and research methods of alternative splicing in plants, as well as the latest research progress of alternative splicing in several plants, and puts forward suggestions on the research direction in the future.

Keywords: mRNA; alternative splicing; plant; Arabidopsis; soybean; single molecule sequencing technology

0引言

可變剪接又稱選擇性剪接(Alternative Splicing, AS),指在一個mRNA前體中通過不同的剪接方式產(chǎn)生不同的mRNA異構(gòu)體的過程。(剩余10791字)

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