中國乙型肝炎疫苗免疫策略及接種進(jìn)展

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摘要：乙型肝炎是全球重要的公共衛(wèi)生問題。我國通過實施以乙型肝炎疫苗為核心的綜合防控策略，在乙型肝炎防控方面取得了顯著成效，但仍存在諸多問題和挑戰(zhàn)。本文回顧了我國乙型肝炎免疫策略的發(fā)展歷程，分析了不同人群的疫苗接種目標(biāo)與進(jìn)展，以及存在的問題及挑戰(zhàn)，為進(jìn)一步優(yōu)化免疫策略和提升防控水平提供參考。

關(guān)鍵詞：乙型肝炎疫苗；免疫；接種；疫苗，聯(lián)合

基金項目：國家自然科學(xué)基金（11571272）

Strategies and advances in hepatitis B vaccination in China

TANG Lin1，2，XU Xia1，2，ZHOU Zemei1，2，WANG Xiaoqi1，2，LIJizhen1，2，YIN Zundong1，2，WANG Fuzhen1，2

1.National Immunization Program，Chinese Center for Disease Control and Prevention，Beijing 100050，China；2.National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases，Chinese Center for Disease Control and Prevention，Beijing 102206，China

Corresponding author：WANG Fuzhen，wangfz@chinacdc.cn（ORCID：0000-0002-6784-7711）

Abstract：Hepatitis B is a major global public health issue.Through the implementation of comprehensive prevention and control strategies centered on hepatitis B vaccination，China has achieved remarkable progress in hepatitis B prevention and control，while there are still many issues and challenges.This article reviews the development of hepatitis B vaccination strategies in China，analyzes the goal and advances in vaccination in different populations，and problems and challenges，in order to provide a reference for further optimizing vaccination strategies and improving the levels of prevention and control.

Key words：Hepatitis B Vaccines；Immunity；Vaccination；Vaccines，Combined

Research funding：National Natural Science Foundation of China（11571272）

乙型肝炎是全球范圍內(nèi)的重大公共衛(wèi)生問題之一。（剩余18759字）