基于數(shù)據(jù)挖掘探討中醫(yī)藥治療老年性白內(nèi)障術(shù)后干眼癥用藥規(guī)律

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[關(guān)鍵詞]干眼癥;老年性白內(nèi)障;術(shù)后;中醫(yī)藥;文獻(xiàn);數(shù)據(jù)挖掘;用藥規(guī)律 [中圖分類號(hào)]R276.7 [文獻(xiàn)標(biāo)志碼]A [文章編號(hào)]0256-7415(2025)11-0001-06 DOl:10.13457/j.cnki.jncm.2025.11.001
Exploration on Medication Rules of Chinese Medicine in the Treatment of Xerophthalmia After Operation for Senile Cataract Based on Data Mining Techniques
HUFangxin1,XU Siting1,YUAN Yuan2,WANG Yan3 1.TheSecond Clinical Medical Schoolof Guangzhou UniversityofChinese Medicine,Guangzhou Guangdong 51006,China; 2.Guangdong Provincial Hospitalof ChineseMedicine,GuangzhouGuangdong 51O120,China;3.Guangdong SecondTraditional Chinese Medicine Hospital,Guangzhou Guangdong 51Oo95,China
Abstract:Objective:To explore the medication rules of Chinese Medicine in the treatment of xerophthalmia after operation for senilecataract based on Traditional Chinese Medicine Inheritance Computing System(TCMICS)V3.5. Methods:Prescriptions for the treatment of xerophthalmia after operation for senile cataract were retrieved fromthe China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform(Wanfang),and China Science and Technology Journal Database(VIP)from the establishment of the databases up to October 31,2024.The TCMICSV3.5 was used to analyze the frequency of medication use,naturesand flavors,channel entry,association rules,and clustering.Results:A total of 198 prescriptions involving 243 diferent Chinese medicines were included. High-frequency Chinesemedicines included Chrysanthemi Flos,Angelicae Sinensis Radix,Poria,Glycyrhizae Radix etRhizoma,and Rehmanniae Radix.The medicinal natures were mainly cold and warm,with flavors primarily sweet,biter,and pungent.The channel entries were mainly liver,lung,and spleen meridians.Clustering analysis identified five groups of herb combinations.Conclusion:Chinese medicine treatment for xerophthalmia afteroperation forsenilecataract primarily focuseson nourishing the liver and kidneys,clearing heat and improving vision,regulating qiand invigorating blood,and strengthening the spleenand draining dampness.The main herbalcompositions are Danggui Shaoyao Powderand Qiju Dihuang Pils.Thissuggests that themain pathogenesisof xerophthalmiaafter operationforsenilecataract involves wind-heat inthe liverandlung withdampnessaffecting theeyes,andqi stagnation with blood stasis.
Keywords:Xerophthalmia;Senile cataract;After operation;Chinese medicine;Literature;Data mining; Medication rules
老年性白內(nèi)障以外科手術(shù)為主,但術(shù)后常伴有干眼癥發(fā)生或加重,對(duì)患者的手術(shù)效果和生活質(zhì)量產(chǎn)生極大影響,阻礙患者的康復(fù)預(yù)后。(剩余6844字)