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運(yùn)動(dòng)康復(fù)改善冠狀動(dòng)脈微循環(huán)障礙的相關(guān)機(jī)制研究進(jìn)展

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【關(guān)鍵詞】冠狀動(dòng)脈微循環(huán)障礙;運(yùn)動(dòng)康復(fù);內(nèi)皮功能障礙;線粒體自噬;血管周圍脂肪組織【中圖分類號(hào)】R331.37【文獻(xiàn)標(biāo)識(shí)碼】A DOI:10.12114/j.issn.1007-9572.2024.0286

【Abstract】Coronary microcirculation disorder refers to the clinical syndrome caused by the abnormal structure and/ orfunctionoftheprecoronaryrteriolesandarterioles,whichiscloselyrelatedtotheprognosisofcardiovasculardiseasessuch asacutecoronarysyndrome,coronaryofender vascularrevascularizationand heartfailure.Asanon-drug intervention for the preventionandtreatmentofcardiovasculardiseases,exerciserehabilitation improves endothelial functionandoxidative inflammationstimulationinpatients withcoronarymicrocirculationdisorders trough signaling molecules,restores mitochondrial autophagylevel,and induces functionalrecoveryofperivascularadiposetissue.Thisarticlereviewedtheresearch progresof exerciseehabilitationinterventionincoronarymicrocirculationdisorder,aimingtoprovidemoreideasandreferencesforexercise rehabilitation treatment of coronary microcirculation disorder.

【Key words】Coronary microcirculationdisorder;Sports rehabilitation;Endothelial dysfunction;Mitochondrial autophagy;Perivascular adipose tissue

隨著冠狀動(dòng)脈造影(CAG)、核素灌注等影像技術(shù)的普及,冠狀動(dòng)脈微循環(huán)障礙(coronarymicrocirculationdisorder,CMD)檢出率逐漸上升。(剩余21956字)

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