川崎病423例臨床特征分析
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Clinical characteristics analysisof 423 cases with Kawasaki disease Fu Minghong，Huang Huiyi， Huang Fengling.Department ofPediatric Cardiology，Quanzhou Women'sandChildren's Hospital，Quanzhou Children's Hospital Fujian ，China
【Abstract】ObjectiveTo investigate and analyze the clinical features of Kawasaki Disease（KD）.Methods Atotalof 423 children with Kawasaki disease who were hospitalized inour hospital from January 2018 to December 2O2O wereselectedas thestudyobjects.Clinicaldataofallchildren were investigated，and C-reactive protein（CRP）andserum procalcitonin （PCT） were detected.The levelsof PCT，D dimer，high-density lipoprotein and serum albumin were analyzed.ResultsAmong the423children，according to theclinical diagnostic criteria， they were divided into a complete group：252 cases with complete Kawasaki disease，accounting for 59.6% ，and anincomplete group：171 cases with incomplete Kawasaki disease，accounting for 39.4% .Theclinical symptoms （neck lymph nodeenlargement，hand-footdisease，conjunctival congestion，oral disease，rash），cardiovascularand nervous system complications and treatment outcomes were statistically significant between the complete group and the incomplete group（ P <0.05）. The white blood cell count，platelet count，haemoglobin and erythrocyte sedimentation rate in the complete group werenot significantly different from those in the incomplete group（ P> （20 0.05）.The levels of serum CRP，PCT and D-dimer in the complete group were higher than those in the incomplete group （ P <0.05），and the contents of high-density lipoprotein and serum albumin in the complete group were lower than those in the incomplete group（ P <0.05）.Logistic regression equation analysis showed that serum CRP，PCT，Ddimer，high-density lipoproteinandserumalbumin levelswereall influential factors leading to the occurrence of complete Kawasaki disease （P
【Key Words】Kawasaki disease;Clinical features；C-reactive protein；Procalcitoni；D dimer;High density lipoprotein;Serum albumin
川崎?。↘awasakidisease，KD）是一種兒童期特有的全身性血管炎癥性疾病，又稱皮膚黏膜淋巴結(jié)綜合 征（mucocutaneous lymph node syndrome，MCLS）主要影響中小動(dòng)脈，尤其是冠狀動(dòng)脈，引發(fā)急性發(fā)熱和多種皮膚黏膜表現(xiàn)1]。（剩余7513字）