誘導(dǎo)多能干細(xì)胞的研究進(jìn)展

【摘要】 對誘導(dǎo)多能干細(xì)胞（induced pluripotent stem cell，iPSC）的應(yīng)用研究從2006年開始已經(jīng)逐漸成為干細(xì)胞研究和臨床治療領(lǐng)域的一個熱門課題。這項(xiàng)技術(shù)的問世為再生醫(yī)學(xué)、疾病建模和醫(yī)藥發(fā)展提供了前所未有的機(jī)會。本文就iPSC的發(fā)展前景和相關(guān)應(yīng)用進(jìn)行綜述。

【關(guān)鍵詞】 誘導(dǎo)多能干細(xì)胞 疾病模型 再生醫(yī)學(xué) 遺傳安全性

Research Progress of Induced Pluripotent Stem Cell/JIANG Yuxiao， YU Hao. //Medical Innovation of China， 2023， 20（20）： -188

[Abstract] The application of induced pluripotent stem cell （iPSC） has gradually become a hot topic in the field of stem cell research and clinical treatment since 2006. The advent of this technology offers unprecedented opportunities for regenerative medicine， disease modeling and pharmaceutical development. This paper reviews the development prospect and related applications of iPSC.

[Key words] Induced pluripotent stem cell Disease model Regenerative medicine Genetic safety

First-author's address： Clinical Medicine Major of Capital Medical University Eighth Clinical School， Beijing 100038， China

doi：10.3969/j.issn.1674-4985.2023.20.042

1981年，研究人員首次從鼠胚胎中提取出一種能不斷增殖并能充分發(fā)育的小鼠胚胎干細(xì)胞（mESCs）。（剩余9174字）