頸源性失眠發(fā)病機(jī)制研究進(jìn)展
摘 要 頸源性失眠的發(fā)病率逐年升高并成為臨床治療熱點(diǎn),本文通過檢索并梳理近年相關(guān)文獻(xiàn),從下丘腦-垂體-腎上腺軸失調(diào)、腦神經(jīng)遞質(zhì)、阿片能信號通路、促炎細(xì)胞因子、運(yùn)動(dòng)節(jié)段囊狀韌帶受壓、肌筋膜觸發(fā)點(diǎn)、社會(huì)環(huán)境和遺傳因素等七個(gè)方面論述頸源性失眠的發(fā)病機(jī)制,為后續(xù)臨床診治進(jìn)一步研究提供指導(dǎo)。
關(guān)鍵詞 頸源性失眠;發(fā)病機(jī)制;研究進(jìn)展
中圖分類號:R749 文獻(xiàn)標(biāo)志碼:A 文章編號:1006-1533(2023)22-0038-03
引用本文 馮蕾, 蔡之幸, 劉帥, 等. 頸源性失眠發(fā)病機(jī)制研究進(jìn)展[J]. 上海醫(yī)藥, 2023, 44(22): 38-40; 57.
基金項(xiàng)目:上海市閔行區(qū)衛(wèi)生健康委員會(huì)科研課題(2021MW42)
Research progress in the pathogenesis of cervical insomnia
FENG Lei1, CAI Zhixing2, LIU Shuai1, LI Fei1, ZHU Danyang2
(1. Department of Traditional Chinese Medicine of Huacao Community Health Service Center of Minhang District, Shanghai 201107, China; 2. Department of Traditional Chinese Medicine of Tongren Hospital of School of Medicine Affiliated to Shanghai Jiao Tong University, Shanghai 200336, China)
ABSTRACT The incidence of cervical insomnia is increasing year by year and has become a hot spot in clinical treatment, this article retrieved and summarized the pathogenesis of cervicogenic insomnia in relevant literatures in recent years from seven aspects, including hypothalamic-pituitary-adrenal axis dysfunction, brain neurotransmitters, opioid signal pathway, proinflammatory cytokines, compression of motor segment cystic ligament, myofascial trigger points, social environment and genetic factors, and provides guidance for further clinical diagnosis and treatment.
KEY WORDS cervical insomnia; pathogenesis; research progress
頸源性失眠主要因頸椎退行性變、外傷或頸部肌肉勞損引起頸部關(guān)節(jié)疼痛、椎動(dòng)脈供血不足及不同程度植物神經(jīng)功能紊亂而導(dǎo)致的入睡困難、早醒、睡眠時(shí)間短、睡眠質(zhì)量差等癥狀[1]。(剩余8579字)