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肝硬化門靜脈高壓伴自發(fā)性門體分流的診治現狀與展望

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摘要: 肝硬化是各種慢性肝病的終末階段,主要的臨床表現為門靜脈高壓,其發(fā)生可導致自發(fā)性門體分流(SPSS)。SPSS在臨床上多見,并且與患者預后息息相關。本文總結了近年來研究肝硬化門靜脈高壓伴SPSS的臨床意義、研究中所存爭議、當前治療現狀以及未來展望與挑戰(zhàn),為門靜脈高壓的規(guī)范化診治提供參考。

關鍵詞: 肝硬化; 高血壓, 門靜脈; 自發(fā)性門體分流

基金項目: 西安市科技計劃項目(23YXYJ0180); 西安醫(yī)學院創(chuàng)新團隊(2021TD15); 佑安肝病感染病??漆t(yī)療聯盟科研專項基金(LM202028)

Diagnosis and treatment of cirrhotic portal hypertension with spontaneous portosystemic shunt: Current statusand prospects

CHEN Yaxin 1,2 , GUO Wen 1,2 , LIU Kaige 1 , LI Qian 1 , ZHANG Mingxin 1

1. Department of Gastroenterology, The First Affiliated Hospital of Xi’an Medical College, Xi’an 710077, China; 2. GraduateSchool of Xi’an Medical University, Xi’an 710021, China

Corresponding author: ZHANG Mingxin, zmx3115@xiyi.edu.cn (ORCID: 0000-0002-3945-3387)

Abstract: Liver cirrhosis is the terminal stage of various chronic liver diseases, with the main clinical manifestation of portalhypertension, which can lead to spontaneous portosystemic shunt (SPSS). SPSS is very common in clinical practice and is closelyassociated with the prognosis of patients. This article summarizes the recent studies in the clinical significance of cirrhotic portalhypertension with SPSS, the controversies in studies, and the current status and future prospects and challenges of treatment, inorder to provide a reference for the standardized diagnosis and treatment of portal hypertension.Key words: Liver Cirrhosis; Hypertension, Portal; Spontaneous Portosystemic ShuntResearch funding: Xi’an Science and Technology Plan Project (23YXYJ0180); The Innovation Team of Xi’an MedicalUniversity (2021TD15); Youan Specialist Medical Alliance for Liver and Infectious Diseases Special Fund (LM202028)

在肝硬化患者中,門靜脈高壓可導致自發(fā)性門體分流(spontaneous portal system shunt,SPSS)發(fā)生。(剩余17727字)

目錄
monitor