胰腺疾病相關(guān)消化不良的診治

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摘要： 各類胰腺疾病均可能引起消化不良，其主要機(jī)制在于胰腺實(shí)質(zhì)損傷和/或胰管阻塞導(dǎo)致胰腺外分泌功能不全，消化功能受損，進(jìn)而引發(fā)營(yíng)養(yǎng)不良、體質(zhì)量下降和預(yù)期生存期縮短等嚴(yán)重臨床后果。因此，臨床上應(yīng)對(duì)胰腺疾病相關(guān)消化不良予以足夠重視，提高其診斷及治療率，以改善胰腺疾病患者的生活質(zhì)量，延長(zhǎng)總體生存期。

關(guān)鍵詞： 胰腺疾?。?消化不良； 胰腺外分泌功能不全

基金項(xiàng)目： 國(guó)家自然科學(xué)基金面上項(xiàng)目（82273426）； 上海市衛(wèi)生健康委員會(huì)科研項(xiàng)目計(jì)劃書(shū)（202240380）

The diagnosis and treatment of pancreatic disease-related dyspepsia

WANG Xiaoyi， FU Deliang

Department of Pancreatic Surgery， Huashan Hospital， Fudan University， Shanghai 200040， China）

Corresponding author： FU Deliang， surgeonfu@163.com （ORCID： 0000-0003-1832-2000）

Abstract： Various pancreatic diseases can cause dyspepsia due to pancreatic exocrine insufficiency （PEI） caused by pancreatic parenchymal injury and/or pancreatic duct obstruction， which further leads to impaired digestive function and a series of severe clinical outcomes such as malnutrition， weight loss， and shortened survival time. Therefore， pancreatic disease-related dyspepsia should be taken seriously in clinical practice to improve its diagnosis and treatment rates， so as to improve the quality of life of patients with pancreatic diseases and prolong overall survival time.

Key words： Pancreatic Diseases； Dyspepsia； Exocrine Pancreatic Insufficiency

Research funding： General Program of National Natural Science Foundation of China （82273426）； General Program of Shanghai Municipal Health Commission （202240380）

胰腺是僅次于肝臟的人體第二大外分泌器官，兼具有內(nèi)、外分泌兩大功能［1］。（剩余10234字）