天麻鉤藤飲加減聯(lián)合鹽酸氟桂利嗪膠囊對(duì)偏頭痛(肝陽(yáng)上亢證)患者頭痛癥狀控制情況的影響

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Effect modified Tianma Gouteng Yincombined with Flunarizine Hydrochloride Capsules on the control headache symptoms inpatients with migraine （liver yang hyperactivity syndrome）Lyu Liuliu，Gao Linxi， Shan Xiao.Department BrainDisease I

【Abstract】 Objective To explore the effct modified Tianma Gouteng Yin combined with Flunarizine Hydrochloride Capsuleson the control headachesymptoms in patients with migraine （liver yang hyperactivity syndrome）.MethodsFrom March 2021 to March 2024，100 patients with migraine （liver yang hyperactivity syndrome） admitted to our hospital were randomly divided into two groups，with 5O cases in each group，using a randomnumber tablemethod.Thecontrol groupwasoralyadministeredFlunarizineHydrochloride Capsules，while theobservation group was treatedwith a modified Tianma Gouteng Drink in combination.Thescores traditional medicine syndrome，clinical efcacy，cerebral blood flowstatus，control headache symptoms，and adverse reactions between the two groups were compared.ResultsThe total efective rate the observation group （96.0% ）was higher than that the control group （82.0% ），withstatistical differences（ P <0.05）. After treatment， theobservation group had lower scores headache andswelling （1.12±0.26），redeyesandbitter mouth （1.07 ± （204號(hào) 0.30），andiritability（1.O2±0.22）compared tothecontrol group.Theaverage bloodflowvelocity theposterior cerebralartery（PCA）（34.22±3.05）cm/s，basilarartery（BA）（25.32±2.11） cm/s，anteriorcerebral artery （ACA） （38.41±2.17）cm/s，and middlecerebral artery （MCA）（42.21±3.18）cm/s werealso lower than those the control group.The duration headache （1.90±0.33）points，the number atacks （2.29±0.22）points，and theseverity （2.13±0.16）points wereallower thanthosethecontrol group.Thecontrol group had low levels，with statistical differences （ P <0.05）.There was no statistically significant diference in the number adverse reactions between the two groups（ P >0.05）. ConclusionIn patients with migraine （liver yang hyperactivity syndrome），the combination Tianma Gouteng Yin modifiedand Flunarizine Hydrochloride Capsules has significanteffects in reducing headache symptoms，improving cerebral blood flow status，and high safety.

【Key Words】Migraine disorders；Tianma Gouteng yin；Flunarizine；Cerebral blood flow status；Headache symptom control status

偏頭痛是一種常見(jiàn)的慢性神經(jīng)血管性疾病，具有家族發(fā)病傾向，其臨床表現(xiàn)主要為反復(fù)發(fā)作的搏動(dòng)性頭痛，通常位于一側(cè)或雙側(cè)頭部，可伴有惡心嘔吐、畏光等自主神經(jīng)功能障礙，嚴(yán)重影響生活質(zhì)量[2]。（剩余5528字）